Figure 5
From: Genes related to emphysema are enriched for ubiquitination pathways
Protein expression of ubiquitination genes in lung tissues from control and COPD patients. Lung homogenates were prepared and Western blotting was performed to examine protein levels with the antibodies specified. β-actin was probed as a protein loading control. Protein levels were quantified by densitometric analysis wit the NIH ImageJ program and normalized to β-actin expression. A: results for FBXL3, FBXO30, and USP38 showing upregulation in COPD. B: results for UBB and RNF6 showing downregulation in COPD. Data are means ± SE, and significance was determined by Students’ t-tests.