Table 3 Hazards ratios and associated 95% CI for CHD, CVD, and all-cause mortality survival models
Model | “Healthy” (n=2107) [L1] | Non-inflammatory COPD (n=1100) [L2] | Inflammatory COPD (n=118) [L3] | CHD only (n=235) [L4] | COPD + CHD (n=121) [L5] | Group comparison p-values | ||
|---|---|---|---|---|---|---|---|---|
[L2] vs [L3] | [L3] vs [L4] | [L4] vs [L5] | ||||||
CHD Mortality | ||||||||
Crude | 1.00 | 3.20 (2.22-4.61) | 7.81 (3.10-19.66) | 18.91 (11.85-30.19) | 23.20 (12.85-41.89) | 0.043 | 0.044 | 0.426 |
Age Adjusted | 1.00 | 1.21 (0.81-1.82) | 2.63 (0.96-7.20) | 6.36 (3.72-10.87) | 6.29 (3.58-11.03) | 0.102 | 0.065 | 0.961 |
Non-modifiable Adjusted | 1.00 | 1.11 (0.75-1.65) | 2.52 (0.92-6.89) | 5.56 (3.24-9.55) | 5.02 (2.83-8.90) | 0.082 | 0.098 | 0.671 |
Full Model | 1.00 | 0.90 (0.61-1.33) | 2.06 (0.84-5.04) | 4.55 (2.48-8.36) | 3.89 (2.28-6.65) | 0.061 | 0.112 | 0.498 |
CVD Mortality | ||||||||
Crude | 1.00 | 3.37 (2.38-4.79) | 6.60 (2.93-14.85) | 14.53 (9.60-22.00) | 18.81 (11.14-31.76) | 0.080 | 0.029 | 0.269 |
Age Adjusted | 1.00 | 1.21 (0.83-1.79) | 2.11 (0.87-5.08) | 4.62 (2.96-7.21) | 4.78 (3.04-7.52) | 0.182 | 0.051 | 0.861 |
Non-modifiable Adjusted | 1.00 | 1.15 (0.78-1.68) | 2.01 (0.84-4.79) | 4.25 (2.70-6.69) | 4.12 (2.60-6.54) | 0.164 | 0.056 | 0.880 |
Full Model | 1.00 | 0.93 (0.62-1.40) | 1.55 (0.68-3.51) | 3.38 (1.97-5.80) | 3.16 (1.99-5.01) | 0.202 | 0.065 | 0.727 |
All-Cause Mortality | ||||||||
Crude | 1.00 | 4.30 (3.51-5.26) | 7.55 (4.65-12.25) | 8.55 (6.61-11.07) | 10.30 (7.21-14.71) | 0.007 | 0.561 | 0.299 |
Age Adjusted | 1.00 | 1.80 (1.44-2.25) | 2.79 (1.63-4.79) | 3.25 (2.59-4.08) | 3.17 (2.33-4.30) | 0.061 | 0.523 | 0.847 |
Non-modifiable Adjusted | 1.00 | 1.70 (1.36-2.12) | 2.72 (1.62-4.56) | 2.96 (2.33-3.76) | 2.72 (1.97-3.74) | 0.037 | 0.701 | 0.546 |
Full Model | 1.00 | 1.39 (1.12-1.74) | 2.01 (1.24-3.28) | 2.48 (1.94-3.16) | 2.19 (1.63-2.95) | 0.096 | 0.373 | 0.348 |