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Figure 2 | BMC Pulmonary Medicine

Figure 2

From: Dose response of umeclidinium administered once or twice daily in patients with COPD: a randomised cross-over study

Figure 2

Observed LS mean trough FEV 1 and simulated fitted model for UMEC QD and BID regimens. Data are for (a) UMEC QD in the mITT population, (b) UMEC QD in the mITT population excluding patients from one investigator site, (c) UMEC BID in the mITT population, and (d) UMEC BID in the mITT population excluding patients from one investigator site. CI, confidence interval; ED50 (C50), dose that yields 50% of Emax; Emax, maximum predicted FEV1 response; FEV1, forced expiratory volume in 1 second; Obs LS, observed least square; RSE, relative standard error.

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