Figure 4From: Dose response of umeclidinium administered once or twice daily in patients with COPD: a randomised cross-over study Serial FEV 1 on Day 7 adjusted treatment differences from baseline. Data are for (a) UMEC QD and tiotropium, and (b) UMEC BID and tiotropium (mITT population). BID, twice daily; CI, confidence interval; LS, least square; QD once daily; Tio, tiotropium.Back to article page