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Table 2 Probability of a dose exceeding a target response (adjusted for placebo) (mITT population)

From: Dose response of umeclidinium administered once or twice daily in patients with COPD: a randomised cross-over study

UMEC dose Probability (%) of exceeding a specified change from baseline FEV1at trough (Day 8 dataset)
0.075 L 0.100 L 0.120 L 0.150 L
15.6 μg QD 43 21 11 3
31.25 μg QD 88 74 56 30
62.5 μg QD 95 87 77 52
125 μg QD 99 100 99 92
15.6 μg BID 89 75 59 33
31.25 μg BID 78 60 44 21
  1. BID, twice daily; FEV1, forced expiratory volume in 1 second; QD, once daily; UMEC, umeclidinium bromide.