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Table 4 Genotypic- phenotypic features in all asthma patients with mild, moderate and severe asthma

From: The effect of CD14 and TLR4 gene polimorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study

 

All asthma patients

p

Atopic

Non-atopic

p

(Standart deviation)

 

Asthmatics (Standart deviation)

Asthmatics (Standart deviation)

 
 

1

2

3

 

(n = 96)

(n = 35)

 
 

(n = 19)

(n = 78)

(n = 34)

    

FEV1 (%)

88

72

51

<0.001

71

62

<0.001

(6.7)

(4.2)

(6.2)

 

(12)

(13)

 

Eosinophil (%)

3.25

4.02

3.61

<0.001

3.84

2.2

0.008

(3)

(3.35)

(2.5)

 

(3.2)

(1.3)

 

Total IgE (kU/L)

170

240

199

0.006

223

47

<0.001

(156)

(255)

(244)

 

(240)

(37)

 

Log IgE median

1.9

2.02

1.7

0.006

2.1

1.5

<0.001

 

(0.5)

(0.6)

(0.6)

 

(0.5)

(0.4)

 

CD14-159

       

 CC

1

14

5

0.27

20

6

0.62

 CT

5

31

7

 

43

19

 

 TT (T Allele)

9

21

3

 

33

10

 

 CC+CT (CAllele)

6

45

12

0.10

63

25

0.68

TLR4 299

       

 AA

14

60

14

0.45

88

34

0.44

 GA

1

6

1

 

8

1

 

TLR4 399

       

 CC

14

58

14

0.23

86

34

0.29

 CT

1

8

1

 

10

1

 
  1. Comperative Features in Atopic and Non-atopic Asthmatics.
  2. 1: Mild asthma; 2: Moderate asthma; 3: Severe asthma. FEV1: Forced expiratory volume 1. Log IgE: Logarithm IgE.
  3. Significant p value is shown with black boldface.