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Table 2 Multivariable predictors of 30-day in-hospital mortality

From: Development of a risk-adjusted in-hospital mortality prediction model for community-acquired pneumonia: a retrospective analysis using a Japanese administrative database

Variables

Adjusted odds ratio (95% CI)

P

Male

1.29 (1.15-1.45)

< 0.001

BMI (reference, ≥18.5 and <25 kg/ m2)

reference

 

 Missing BMI dataa

1.93 (1.66-2.24)

< 0.001

 <18.5 kg/m2

1.55 (1.36-1.77)

< 0.001

 ≥25 kg/m2

0.79 (0.63-0.97)

0.028

Age (reference, 15–64 y)

reference

 

 65–74 y

2.08 (1.55-2.79)

< 0.001

 75–84 y

3.26 (2.50-4.25)

< 0.001

 ≥85 y

5.25 (3.99-6.91)

< 0.001

BUN ≥7.5 mmol/L or Dehydration

1.88 (1.67-2.12)

< 0.001

SpO2 (reference >90%, room air)

reference

 

 FiO2 < 35%b (without Ventilator)

2.40 (2.09-2.75)

< 0.001

 FiO2 ≥ 35%b (without Ventilator)

6.63 (5.61-7.82)

< 0.001

 Ventilatorc

7.55 (6.00-9.52)

< 0.001

Orientation (reference JCS 0)

reference

 

 JCS 1-3

1.65 (1.43-1.90)

< 0.001

 JCS 10-30

2.86 (2.30-3.55)

< 0.001

 JCS 100-300

4.21 (3.20-5.53)

< 0.001

Systolic BP (reference > 90 mmHg)

reference

 

 ≤90 mmHg (without Vasopressor)

2.96 (2.51-3.49)

< 0.001

 Vasopressorc

4.24 (3.27-5.48)

< 0.001

CRP 200 mg/L or extent of consolidation on chest X-ray ≥2/3 of one lung

2.27 (2.00-2.58)

< 0.001

Comorbidities

 Cancer

2.25 (1.93-2.63)

< 0.001

 Liver disease

1.38 (0.76-2.51)

0.286

 Kidney (reference free)

reference

 

  Renal disease (without Hemodialysis)

1.20 (0.94-1.55)

0.149

  Hemodialysisc

1.55 (0.95-2.54)

0.080

 Congestive heart failure

1.43 (1.26-1.61)

< 0.001

 Cerebrovascular disease

0.84 (0.68-1.02)

0.081

 Immune deficiency

1.45 (1.20-1.76)

< 0.001

Emergency admission via ambulance

1.50 (1.33-1.69)

< 0.001

c-statistic

0.894 (0.888-0.900)

< 0.001

  1. Abbreviations: CI, confidence interval; BMI, body mass index; BUN, blood urea nitrogen; SpO2, pulse oximetry saturation; FiO2, fraction of inspired oxygen; JCS, Japan Coma Scale; BP, blood pressure; CRP, C-reactive protein.
  2. aBMI data missing: BMI data were missing in 4,698/35,297 pneumonia patients.
  3. bFiO2 < 35% and ≥35%: fraction of inspired oxygen (<35% and ≥35%, respectively) required to maintain SpO2 > 90%.
  4. cVentilator and vasopressor treatments were started within 2 days of admission. Hemodialysis was started within 3 days of admission.