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Table 3 Biochemical and hematological parameters of 12 outpatients with COPD, before and after treatment with ESAs and intravenous iron

From: Anemia and iron deficiency in COPD patients: prevalence and the effects of correction of the anemia with erythropoiesis stimulating agents and intravenous iron

Characteristics

Baseline

After treatment

p

Weight kg

77.2 [69.2–90.5]

77.9 [70.2–88.1]

0.32

DBP mmHg

67.5 [60–88]

70.1 [66–85]

0.19

SBP mmHg

138 [ 120–158]

134 [121–156]

0.05

Hb g/dl [11.7–15.5]

9.9 [9.2–10.6]

12.4 [11.6–13]

0.0005

Hct% [35–45]

29.9 [28–31.5]

38.1 [35.0–39.4]

0.0005

MCV fl [80–96]

89.0[85–92]

90 [87–92]

0.17

RBC 106/μl 4.3–5.8

3.3 [3.2–3.7]

3.9 [3.6–4.3]

0.01

MCH pg [26–34]

30.5 [29.3–31.7]

29.8 [29.0–31.6]

0.99

MCHC g/dl [31–37]

33.3 [32.6–34.2]

33.4 [32.9–34.3]

0.8

RDW%

14.9 [13.1–16.5]

15.4 [14.6–16.5]

0.13

WBC`103/ul [4–11]

8.0 [4.9–9.2]

7.1 [6.0–8.3]

0.38

Lymphocytes% WBC [20–40]

19.2 [16.1–21.0]

21.0 [18.0–23.9]

0.6

Platelets 103/μl [150–450]

237 [193–303]

220 [170–282]

0.51

TSAT% [20–55]

12.8 [11.0–19.1]

24.0 [18.5–27.9]

0.005

Ferritin ng/ml [220–400]

99 [48.6–127.4]

330.6 [243.4–615.2]

0.005

Iron mcg/dl [40–150]

44,5 [29–61]

61.5 [57–74]

0.015

Serum creatinine mg/dl [0.7–1.3]

2.4 [1.8–3.6]

2.4 [1.9–3.5]

0.21

eGFR ml/min/1.73 m2 [ > 90]

27.5 [19–37]

28.50 [21–39]

0.56

GOT U/l [7–40]

20 [17–39]

26 [15–41]

0.04

GPT U/l [5–39]

16 [11–41]

21 [10–40]

0.04

Albumin g/l [35–50]

38.5 [36–42]

39.0 [35–41]

0.36

VAS [0–10]

2.5 [2–3]

8.5 [7–10]

0.0005

  1. Values are presented as median with interquartile range [IQR] and reference intervals.
  2. Abbreviations: DBP, diastolic blood pressure; eGFR, estimate glomerular filtration rate; ESAs, erythropoiesis stimulating agents; GOT, alanine amino-transferase; GPT, aspartate amino-transferase; Hb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RBC, red blood cell count; RDW, red cell distribution width; SBP, systolic blood pressure; VAS, Visual Analogue Scale; WBC, white blood cell count; %TSat, % transferrin saturation.