Skip to main content

Table 3 Biochemical and hematological parameters of 12 outpatients with COPD, before and after treatment with ESAs and intravenous iron

From: Anemia and iron deficiency in COPD patients: prevalence and the effects of correction of the anemia with erythropoiesis stimulating agents and intravenous iron

Characteristics Baseline After treatment p
Weight kg 77.2 [69.2–90.5] 77.9 [70.2–88.1] 0.32
DBP mmHg 67.5 [60–88] 70.1 [66–85] 0.19
SBP mmHg 138 [ 120–158] 134 [121–156] 0.05
Hb g/dl [11.7–15.5] 9.9 [9.2–10.6] 12.4 [11.6–13] 0.0005
Hct% [35–45] 29.9 [28–31.5] 38.1 [35.0–39.4] 0.0005
MCV fl [80–96] 89.0[85–92] 90 [87–92] 0.17
RBC 106/μl 4.3–5.8 3.3 [3.2–3.7] 3.9 [3.6–4.3] 0.01
MCH pg [26–34] 30.5 [29.3–31.7] 29.8 [29.0–31.6] 0.99
MCHC g/dl [31–37] 33.3 [32.6–34.2] 33.4 [32.9–34.3] 0.8
RDW% 14.9 [13.1–16.5] 15.4 [14.6–16.5] 0.13
WBC`103/ul [4–11] 8.0 [4.9–9.2] 7.1 [6.0–8.3] 0.38
Lymphocytes% WBC [20–40] 19.2 [16.1–21.0] 21.0 [18.0–23.9] 0.6
Platelets 103/μl [150–450] 237 [193–303] 220 [170–282] 0.51
TSAT% [20–55] 12.8 [11.0–19.1] 24.0 [18.5–27.9] 0.005
Ferritin ng/ml [220–400] 99 [48.6–127.4] 330.6 [243.4–615.2] 0.005
Iron mcg/dl [40–150] 44,5 [29–61] 61.5 [57–74] 0.015
Serum creatinine mg/dl [0.7–1.3] 2.4 [1.8–3.6] 2.4 [1.9–3.5] 0.21
eGFR ml/min/1.73 m2 [ > 90] 27.5 [19–37] 28.50 [21–39] 0.56
GOT U/l [7–40] 20 [17–39] 26 [15–41] 0.04
GPT U/l [5–39] 16 [11–41] 21 [10–40] 0.04
Albumin g/l [35–50] 38.5 [36–42] 39.0 [35–41] 0.36
VAS [0–10] 2.5 [2–3] 8.5 [7–10] 0.0005
  1. Values are presented as median with interquartile range [IQR] and reference intervals.
  2. Abbreviations: DBP, diastolic blood pressure; eGFR, estimate glomerular filtration rate; ESAs, erythropoiesis stimulating agents; GOT, alanine amino-transferase; GPT, aspartate amino-transferase; Hb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RBC, red blood cell count; RDW, red cell distribution width; SBP, systolic blood pressure; VAS, Visual Analogue Scale; WBC, white blood cell count; %TSat, % transferrin saturation.