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Table 2 Associations between YKL-40 and pulmonary inflammation and infection

From: Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease

Variable

YKL-40 in BAL

YKL-40 in serum

β

SE

r2

p

β

SE

r2

p

BAL macrophages (×103/ml fluid)

0.98

0.20

0.34

<0.001

0.10

0.11

0.02

0.34

BAL neutrophils (×103/ml fluid)

0.58

0.07

0.74

<0.001

−0.003

0.04

0.0002

0.92

NE (ng/ml)

0.45

0.06

0.47

<0.001

−0.02

0.04

0.004

0.61

CXCL8 (pg/ml)

0.49

0.07

0.45

<0.001

−0.03

0.05

0.01

0.55

IL-1β (pg/ml)

0.64

0.06

0.62

<0.001

0.08

0.04

0.04

0.052

IL-6 (pg/ml)

0.40

0.21

0.14

0.060

−0.03

0.08

0.005

0.69

Respiratory symptoms at BAL

0.36

0.40

0.06

0.366

−0.10

0.17

0.005

0.57

Pulmonary infection

        

• Any

1.30

0.34

0.17

<0.001

0.33

0.19

0.06

0.083

P. aeruginosa

1.21

0.41

0.20

0.003

0.33

0.15

0.06

0.024