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Figure 3 | BMC Pulmonary Medicine

Figure 3

From: Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation

Figure 3

N6022 increased BALF nitrite. OVA-sensitized mice were treated with a single i.v. dose of either N6022 or PBS vehicle administered 24 h prior to MCh challenge which was one hour prior to the last OVA airway challenge. Non-sensitized mice treated with a single i.v. dose of PBS at 24 h prior to MCh challenge (one hour prior to OVA) also were assessed. Nitrite levels in BALF were measured via ozone chemiluminescence. Bars are the means ± SEM of 6 mice per group. *p < 0.05 for N6022 vs. vehicle, One-way ANOVA, Dunnett’s.

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