Table 2 Lung function data of patients and controls

Forced vital capacity (FVC) (L)

3.84 (0.94)

3.10 (1.08)

NS

2.95 (0.98)

NS

2.98 (0.69)

NS

FVC (% of pred.)

98.56 (12.00)

80.27 (15.61)

<0.005

76.75 (19.8)

0.003

91.13 (14.39)

NS

Forced expiratory volume in 1 s (FEV1 (L)

2.93 (0.78)

2.46 (0.84)

NS

1.24 (0.56)

<0.001

2.36 (0.55)

NS

FEV1 (% of pred.)

94.19 (15.58)

79.40 (14.49)

NS

39.81 (15.19)

<0.001

90.4 (16.27)

NS

FEV1/FVC (%)

0.76 (0.07)

0.80 (0.08)

NS

0.42 (0.11)

<0.001

0.80 (0.05)

NS

FEV1/FVC% (% of pred.)

94.38 (8.96)

99.67 (10.70)

NS

52.38 (13.80)

<0.001

99.6 (7.13)

NS

Peak expiratory flow (PEF) (L/s)

7.80 (1.73)

7.43 (2.84)

NS

3.43 (1.58)

<0.001

6.6 (1.38)

NS

PEF (% of pred.)

93.44 (16.08)

91.53 (24.56)

NS

41.56 (18.86)

<0.001

95.1 (21.09)

NS

MEF50 (% of pred.)

73.38 (31.71)

81.60 (29.71)

NS

12.25 (8.44)

<0.001

73.9 (26.2)

NS

MEF25 (% of pred.)

95.19 (52.52)

94.07 (51.77)

NS

23.77 (14.62)

<0.001

88.07 (30.92)

NS

Rtot (% of pred.)

129.44 (37.02)

168.27 (60.32)

NS

327.02 (176.1)

0.003

149.0 (36.8)

NS

sGtot (% of pred.)

90.75 (29.48)

98.53 (48.37)

NS

31.81 (16.25)

<0.001

81.13 (24.1)

NS

FRCpleth (Functional recidual capacity by plethysmograph (L)

3.86 (0.60)

2.77 (0.73)

<0.001

5.17 (1.13)

NS

2.46 (0.41)

<0.001

FRCpleth (% of pred.)

104.62 (14.14)

77.07 (15.70)

<0.001

129.2 (29.2)

0.007

89.5 (11.4)

NS

TLC (Total lung capacity) (L)

6.88 (1.18)

5.12 (1.32)

<0.001

7.38 (1.34)

NS

5.43 (0.89)

<0.005

TLC (% of pred.)

102.94 (12.08)

78.67 (13.66)

<0.001

111.23 (14.00)

NS

96.9 (8.79)

NS

RV (residual capacity) (L)

2.49 (0.37)

1.8 (0.33)

<0.001

3.86 (0.97)

0.002

2.02 (0.46)

NS

RV (% of pred.)

97.1 (16.2)

73.67 (12.3)

<0.001

150.8 (48.71)

0.004

95.2 (17.2)

NS

ERV (Expiratory reserve volume) (L)

1.37 (0.63)

0.97 (0.47)

NS

1.47 (0.56)

NS

0.47 (0.33)

<0.001

ERV (% of pred.)

121.4 (45.7)

85.8 (33.0)

NS

102.8 (36.1)

NS

71.3 (42.3)

NS

Trapped air (TLCb – TLC He) (L)

0.82 (0.36)

0.82 (0.38)

NS

2.08 (1.16)

0.004

0.71 (0.37)

NS

DLCOc (Single-breath diffusing capacity for carbon monoxide) (% of pred.)

93.9 (11.3)

51.1 (15.1)

<0.001

38.1 (16.9)

<0.001

85.9 (12.7)

NS

DLCOc/VA (Specific diffusing capacity) (% of pred.)

97.9 (8.4)

73.1 (15.3)

<0.001

45.3 (16.9)

<0.001

97.5 (15.8)

NS