Variable at diagnosis of sPAP | (n) | 75% of OS (months) | 50% of OS (months) | HR (95% CI) | Pvalue |
---|---|---|---|---|---|
Age: 51 yrs or younger | 16 | 8 | 16 | ||
   Older than 52 yrs | 15 | 10 | 15 | 1.29 (0.48-3.41) | 0.607 |
Gender: Male | 19 | 10 | 16 | ||
    Female | 12 | 11 | 21 | 1.12 (0.43-2.94) | 0.804 |
MDS group: mild | 13 | 10 | 15 | ||
      severe | 18 | 11 | 16 | 1.11 (0.42-2.95) | 0.830 |
Symptoms: (-) | 5 | 26 | 26 | ||
     (+) | 26 | 6 | 15 | 1.50 (0.33-6.65) | 0.592 |
Dx procedure: Bronchoscopy | 23 | 11 | 13 | ||
      Surgical biopsy | 8 | 15 | 26 | 0.69 (0.23-2.04) | 0.507 |
Respiratory failure: (-) | 21 | 11 | 26 | ||
         (+) | 10 | 5 | 10 | 2.18 (0.77-6.22) | 0.142 |
Use of corticosteroid: (-) | 16 | 16 | 80 | ||
         (+) | 15 | 10 | 13 | 3.20 (1.09-9.38) | 0.034 |
Serum KL-6 (U/ml): < 1960 | 16 | 13 | 26 | ||
         1960 ≦ | 15 | 5 | 15 | 1.52 (0.58-4.00) | 0.389 |
Serum SP-D (ng/ml): < 147 | 15 | 10 | 26 | ||
         147 ≦ | 15 | 8 | 15 | 1.80 (0.62-5.22) | 0.278 |
Serum SP-A (ng/ml): < 79 | 16 | 11 | 26 | ||
         79 ≦ | 14 | 5 | 15 | 2.79 (0.965-8.06) | 0.058 |
%VC: 87 ≦ | 11 | 15 | 34 | ||
    < 87 | 11 | 8 | 15 | 3.27 (0.79-13.52) | 0.101 |
FEV1%: 86 ≦ | 12 | 8 | 16 | ||
     < 86 | 10 | 13 | 34 | 0.52 (0.14-1.87) | 0.322 |
%DLco: 44 ≦ | 9 | 21 | 34 | ||
     < 44 | 8 | 5 | 13 | 9.98 (1.03-96.11) | 0.046 |