Prevalent cases n = 100 | Incident cases n = 91 | p† | |
---|---|---|---|
Female sex, n (%) | 65 (65.0) | 60 (65.9) | 0.892 |
NYHA FC | 0.229‡ | ||
I + II, n (%) | 34 (34.0) | 21 (23.1) | |
III, n (%) | 64 (64.0) | 67 (73.6) | |
IV, n (%) | 2 (2.0) | 3 (3.3) | |
Age * (years) | 47.0 (17.0) 47.8 (34.5–60.7/19.4–73.8) | 57.3 (15.1)† 59.8 (48.9–68.8/27.4–75.7) | <0.001 |
BMI * (kg/m2) | 26.2 (5.4) 26.0 (21.8–29.7/18.3–35.9) | 27.8 (6.3) 26.5 (23.2–31.9/19.5–37.9) | 0.100 |
6MWD * (m) | 332.4 (123.0) 356.0 (246.0–420.0/150.0–511.0) | 314.0 (117.0) 332.5 (239.0–403.0/128.0–474.0) | 0.313 |
RAP * (mmHg) | 10.0 (5.3) 9.0 (7.0–12.0/3.0–20.0) | 9.8 (5.2) 9.0 (6.0–12.0/2.0–21.0) | 0.934 |
mPAP * (mmHg) | 65.8 (84.8) 56.5 (46.0–66.0/32.0–89.0) | 51.8 (19.7)† 47.0 (37.0–64.0/27.0–91.0) | 0.004 |
PASP * (mmHg) | 88.2 (24.6) 91.0 (70.0–103.0/45.0–134.0) | 80.7 (28.5)† 77.0 (58.0–97.0/40.0–132.0) | 0.017 |
PCWP * (mmHg) | 10.5 (3.2) 11.0 (8.0–13.0/5.0–15.0) | 11.9 (3.1)† 12.0 (10.0–15.0/7.0–15.0) | 0.003 |
Cardiac index * (l/min/m2) | 1.9 (0.7) 1.7 (1.3–2.4/0.8–3.3) | 2.4 (0.8)† 2.4 (1.9–2.9/1.1–3.9) | <0.001 |
CO * (l/min) | 3.4 (1.5) 3.2 (2.3–4.3/1.6–6.4) | 4.3 (1.6)† 3.9 (3.2–5.4/2.1–7.1) | <0.001 |
SvO 2 * (%) | 92.5 (5.5) 94.5 (90.2–96.4/78.0–98.1) | 91.7 (6.8) 93.5 (89.9–96.2/79.0–98.0) | 0.461 |
SvO 2 * (%) | 66.4 (7.5) 66.0 (61.0–72.0/55.8–78.7) | 70.0 (8.6)† 72.0 (64.6–76.0/56.0–81.2) | 0.002 |
LVEF * (%) | 60.9 (8.4) 61.5 (55.0–67.0/46.0–74.0) | 59.3 (7.5) 58.0 (55.0–64.0/45.0–72.0) | 0.199 |
PAR * (WU) | 20.1 (31.1) 16.0 (9.3–21.4/4.2–42.2) | 10.8 (7.1)† 8.5 (5.6–15.2/3.0–25.8) | <0.001 |
S-creatinine * (μmol/l) | 95.3 (43.1) 88.7 (71.6–99.0/59.1–173.5) | 97.2 (49.8) 81.2 (71.0–104.0/56.0–193.0) | 0.895 |
Creatinine clearance * (ml/min) | 90 (30) 84 (66–108/42–144) | 78 (36) 78 (60–96/30–138) | 0.186 |