Figure 2

Receiver operating characteristic curve for serum levels of heat shock protein (HSP) 47 in patients with various interstitial pneumonias. Highest diagnostic accuracy cut-off level for HSP47 was 859.3 pg/mL, which discriminated between AIP and the other IIPs studied and healthy volunteers with 100% sensitivity, 98.5% specificity, and a diagnostic accuracy of 98.7%. Use of serum HSP47 level for diagnosis of AIP resulted in the area under the curve of 1.000.