Table 1 Study demographics

Age (yrs)

Mean

26

21

23

22

23

SD

6

1

3

2

4

^aBMI (kg/m²)

Mean

23.1

23.4

21.7

21.6

22.5

SD

1.7

1.8

2.2

1.1

1.8

^aWeight (kg)

Mean

73.8

80.3

70.7

70.0

73.7

SD

6.8

8.1

7.4

4.7

7.6

JMAD, healthy subjects

n = 6

400 μg n = 6

1000 μg n = 6

–

n = 18

Age (years)

Mean

Mean 29.8

29.0

27.5

–

28.8

SD

4.9

4.0

3.4

–

4.0

^aBMI (kg/m²)

Mean

21.0

20.7

20.6

–

20.8

SD

1.2

2.3

1.4

–

1.6

^aWeight (kg)

Mean

61.3

63.6

61.4

–

62.1

SD

4.3

7.7

5.5

–

5.8

GMAD, COPD patients

n = 1

–

1000 μg n = 3

–

n = 4

Age (yrs)

Mean

71

–

64

–

66

SD

NC

–

7

–

6

^aBMI (kg/m²)

Mean

23.0

–

27.8

26.6

SD

NC

–

4.0

4.0

^aWeight (kg)

Mean

77.1

–

73.9

–

74.7

SD

NC

–

8.1

–

6.8

^bFEV₁ (L)

Mean

1.62

–

1.48

–

1.52

SD

NC

–

0.53

–

0.43

^bFEV₁ (% predicted)

Mean

48.80

–

64.63

–

60.67

SD

NC

–

17.82

–

16.57

^bFEV₁/FVC (%)

Mean

31.95

–

49.45

–

45.08

SD

NC

–

5.66

–

9.90

Smoking history (%)

Current

1 (100)

–

2 (67)

3 (75)

Former

0 (0)

1 (33)

1 (25)

Years since diagnosis

Mean

5

10

9

SD

NC

9

8