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Table 2 Indices of MOP, CO 2 rebreathing and the UCSD dyspnea score[18] of 73 SSc patients

From: Increased respiratory drive relates to severity of dyspnea in systemic sclerosis

 

V’E/P0.1 < 8 l/min/cmH2O N = 28

V’E/P0.1 ≥ 8 l/min/cmH2O N = 45

P value*

UCSD SOBQ

13 (3.5)

2.2 (2.7)

<0.001

P0.1

1.60 (0.57)

1.10 (0.31)

<0.001

V’E

8.7 (2.3)

11.6 (3.5)

<0.001

V’E/P0.1

5.68 (1.24)

10.83 (2.46)

<0.001

∆V’E/∆PetCO2

2.31 (2.0)

2.49 (1.76)

0.71

(∆V’E/FVC)/∆PetCO2

0.93 (0.72)

0.57 (0.51)

0.07

∆P0.1/∆PetCO2

0.75 (0.42)

0.45 (0.19)

0.01

  1. *P value expressed for student T-test.
  2. UCSD SOBQ (shortness of breath questionnaire; score range 0–120).
  3. P0.1 (mouth occlusion pressure at 0.1 second; cmH 2 O).
  4. V’E (minute ventilation; L/min).
  5. V’E/P0.1 (central inspiratory neuromuscular respiratory drive; L/min/cmH 2 O).
  6. ∆V’E/∆PetCO 2 (hyperoxic ventilatory response to hypercapnia; L/min/mmHg).
  7. (∆V’E/FVC)/∆PetCO 2 (hyperoxic ventilatory response to hypercapnia, corrected for FVC; FVC/min/mmHg).
  8. ∆P0.1/∆PetCO 2 (slope of occlusion pressure to hypercapnia; cmH 2 O/mmHg).
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BMC Pulmonary Medicine

ISSN: 1471-2466

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