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Table 3 Prevalence (with 95% confidence intervals) of respiratory symptoms at baseline in total baseline population, population at 10-yrs follow-up and population at 20-yrs follow-up, and differences between these groups given as ratios of baseline symptom prevalence (with bootstrapped 95% confidence intervals) in population at 10-yrs follow-up over total baseline population, and in population at 20-yrs follow-up over total baseline population a

From: Longterm follow-up in European respiratory health studies – patterns and implications

  

Baseline population (95%CI)

10-yrs follow-up population (95%CI)

Ratio of prevalences (95%CI) b

20-yrs follow-up population (95%CI)

Ratio of prevalences (95%CI) b

Wheeze

RHINE

22.2% (20.4, 21.6)

21.5% (19.9, 21.3)

0.97 (0.95, 0.99)

20.5% (19.0, 20.6)

0.92 (0.90, 0.95)

 

Italian ECRHS

10.0% (9.0, 10.5)

10.2% (8.9, 10.8)

1.02 (0.96, 1.07)

10.1% (8.0, 11.2)

1.01 (0.87, 1.14)

 

ISAYA

15.1% (12.4, 14.6)

13.7% (11.1, 13.8)

0.91 (0.84, 0.98)

-

-

Asthma

RHINE

4.7% (4.3, 5.0)

4.8% (4.4, 5.2)

1.02 (0.99, 1.05)

4.6% (4.3, 5.1)

0.98 (0.92, 1.03)

 

Italian ECRHS

4.2% (3.6, 4.6)

4.2% (3.5, 4.7)

1.00 (0.91, 1.09)

3.8% (2.5, 4.5)

0.90 (0.67, 1.10)

 

ISAYA

5.3% (4.4, 5.8)

5.0% (3.8, 5.6)

0.94 (0.83, 1.07)

-

-

Rhinitis

RHINE

19.3% (19.3, 20.5)

19.8% (19.7, 21.1)

1.03 (1.01, 1.04)

19.9% (19.9, 21.5)

1.03 (1.00, 1.06)

 

Italian ECRHS

15.9% (14.8, 16.6)

15.8% (14.4, 16.7)

0.99 (0.95, 1.03)

18.2% (15.8, 20.0)

1.14 (1.02, 1.26)

 

ISAYA

20.7% (19.3, 21.8)

21.1% (19.3, 22.7)

1.02 (0.96, 1.08)

-

-

  1. aTotal baseline population: participants in 1989–92 in RHINE, 1991–93 in Italian ECRHS, 1998–2000 in ISAYA. 10-yrs follow up population: participants in 1999-2000 in RHINE and 1998–2000 in Italian ECRHS, 2008–09 in ISAYA. 20-yrs follow-up population: participants in 2010-12 in RHINE, 2008–09 in Italian ECRHS.
  2. bCorrected for inter-dependency between long-term participants and total baseline participants, by using a non-parametric bootstrap method. Significant differences between long-term participants and all baseline participants are marked in bold font.