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Table 4 Peak and late inspiratory and expiratory flow of the lung (PIF, LIF, PEF, LEF) during different parts of the respiratory cycle in different regions-of-interest (ROI)

From: Determination of respiratory gas flow by electrical impedance tomography in an animal model of mechanical ventilation

PIF Phase 1 Inspiration   Global ROI Ventral ROI$/§ Middle ROI Dorsal ROI
PEEP [mbar] VT/weight [ml/kg] Lung n Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s]
0 15 healthy 7 467.27 ± 56.69 109.87 ± 15.45 317.60 ± 34.38 298.54 ± 120.62
0 20 healthy 7 571.94 ± 100.47 126.10 ± 17.69 345.79 ± 54.36 327.13 ± 127.57
5 15 healthy 7 510.92 ± 102.16 116.04 ± 14.20 324.25 ± 73.59 334.11 ± 135.32
5 20 healthy 7 621.80 ± 85.20 129.70 ± 16.65 396.75 ± 50.78 348.89 ± 139.71
10 15 healthy 7 550.89 ± 82.35 105.82 ± 13.13 335.46 ± 48.16 339.63 ± 132.18
10 20 healthy 7 711.67 ± 104.68 123.85 ± 22.84 424.07 ± 84.16 402.98 ± 143.06
5 15 healthy 6 901.90 ± 92.06 118.94 ± 32.59 512.73 ± 81.67 283.00 ± 59.44
5 15 LAV 6 968.55 ± 64.49 158.94* ± 24.26 602.78* ± 91.51 335.89 ± 83.67
LIF Phase 2 Inspiration   Global ROI Ventral ROI $ Middle ROI Dorsal ROI
PEEP [mbar] V T /weight [ml/kg] Lung n Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s]
0 15 healthy 7 72.04 ± 16.52 10.26 ± 5.27 36.77 ± 28.00 19.03 ± 4.99
0 20 healthy 7 86.66 ± 36.51 10.80 ± 4.08 43.22 ± 24.84 17.66 ± 4.93
5 15 healthy 7 55.58 ± 23.32 5.65 ± 4.35 18.02 ± 3.12 16.05 ± 4.31
5 20 healthy 7 52.11 ± 10.05 9.50 ± 4.76 27.59 ± 15.06 10.45 ± 5.20
10 15 healthy 7 47.17 ± 16.57 7.83 ± 3.67 23.31 ± 8.22 11.93 ± 9.44
10 20 healthy 7 64.37 ± 45.81 8.69 ± 4.00 32.91 ± 5.27 18.07 ± 15.34
5 15 healthy 6 13.58 ± 2.70 4.03 ± 0.52 18.55 ± 8.65 12.72 ± 5.84
5 15 LAV 6 19.09* ± 5.14 2.82 ± 1.83 10.74* ± 5.29 13.02 ± 3.73
PEF Phase 3 Expiration   Global ROI Ventral ROI $/§ Middle ROI Dorsal ROI
PEEP [mbar] V T / weight [ml/kg] Lung n Meann ± msd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s]
0 15 healthy 7 -587.38 ± 86.73 -130.15 ± 21.79 -360.79 ± 60.67 -344.81 ± 140.78
0 20 healthy 7 -687.01 ± 138.84 -141.14 ± 24.29 -419.64 ± 68.85 -360.89 ± 135.22
5 15 healthy 7 -609.64 ± 164.78 -122.24 ± 16.87 -359.02 ± 71.82 -351.49 ± 156.67
5 20 healthy 7 -675.96 ± 142.03 -119.51 ± 20.03 -397.41 ± 67.45 -413.33 ± 170.68
10 15 healthy 7 -581.72 ± 119.23 -107.19 ± 13.15 -356.31 ± 53.46 -353.22 ± 127.59
10 20 healthy 7 -685.25 ± 114.72 -108.40 ± 13.30 -395.27 ± 41.11 -383.60 ± 152.15
5 15 healthy 6 -666.61 ± 62.94 -94.05 ± 12.91 -373.52 ± 74.09 -257.96 ± 47.51
5 15 LAV 6 -734.43* ± 44.74 -130.40* ± 26.63 -441.15 ± 102.11 -349.22 ± 145.95
LEF Phase 4 Expiration   Global ROI Ventral ROI $ Middle ROI § Dorsal ROI
PEEP [mbar] V T / weight [ml/kg] Lung n Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s] Mean ± sd [ml/s]
0 15 healthy 7 -40.23 ± 25.65 -5.74 ± 4.36 -27.25 ± 14.37 -7.11 ± 5.85
0 20 healthy 7 -58.85 ± 30.50 -8.73 ± 4.94 -48.72 ± 19.19 -16.04 ± 7.86
5 15 healthy 7 -50.20 ± 17.22 -5.41 ± 4.37 -27.87 ± 8.07 -3.74 ± 1.78
5 20 healthy 7 -62.46 ± 37.63 -5.46 ± 2.57 -47.50 ± 13.66 -16.79 ± 10.81
10 15 healthy 7 -49.84 ± 37.89 -3.77 ± 2.04 -23.78 ± 22.54 -9.10 ± 11.72
10 20 healthy 7 -86.42 ± 27.98 -6.67 ± 3.74 -51.34 ± 15.72 -15.81 ± 5.00
5 15 healthy 6 -39.16 ± 23.89 -5.71 ± 3.26 -26.44 ± 10.16 -8.36 ± 4.09
5 15 LAV 6 -36.15 ± 27.84 -6.29 ± 2.20 -20.37 ± 16.26 -2.63* ± 1.00
  1. PEEP: positive end-expiratory pressure. VT/weight: tidal volume per body weight. sd: standard deviation. LAV: lavage injury. Statistical analysis (two-way ANOVA): *p <0.05: comparison to condition above. ROI analysis: $p < 0.05 comparison to middle ROI, §p < 0.05 comparison to dorsal ROI.