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Table 3 Cardiopulmonary exercise tests in CF patients classified according to FEV 1

From: Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease

  All patients (n = 102) Group 1 (n = 48) Group 2 (n = 54)
FEV1   < 50% ≥ 50%
VO2 peak, mL/kg/min 25 ± 9 20 ± 5d 30 ± 8.5
VO2 peaka 65 ± 21 51 ± 13d 77 ± 20
Borg dyspnea 4.7 ± 1.9 5.6 ± 2b 4.1 ± 1.5
Borg Leg fatigue 4.5 ± 1.8 5.2 ± 1.8b 4.4 ± 1.7
VE peak, L/min 58 ± 22 44 ± 11d 70 ± 21
RR peak, min 41 ± 9 43 ± 9b 39 ± 8
VT/FVC peak, % 48 ± 11 47 ± 13 48.6 ± 8
VE/VO2 peak 41 ± 7 42 ± 7 41 ± 7
VE/VCO2 peak 36 ± 6 37 ± 6 35 ± 5
BR, % 24 ± 20 8 ± 11d 37.5 ± 16
VD/VT peak 0.32 ± 0.11 0.39 ± 0.07d 0.25 ± 0.10
pH peak 7.34 ± 0.04 7.34 ± 0.04 7.35 ± 0.04
PaO2 peak, mm Hg 76 ± 16 63 ± 10d 89 ± 12
PaCO2 peak, mm Hg 40 ± 7 44 ± 6d 36 ± 4
P(A-a)O2 peak, mm Hg 37 ± 13 46 ± 8d 28 ± 10
Lactatemia peak, mmol/L 7 ± 2.6 6 ± 2d 7.9 ± 3
HR peaka 82 ± 10 79 ± 8d 86 ± 9
VO2/HR peaka 79 ± 22 67 ± 16d 90 ± 21
  1. aResults are expressed as mean ± SD percentage of predicted values.
  2. b P < .01 compared with group 2.
  3. c P < .001 compared with group 2.
  4. d P < .0001 compared with group 2.