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Table 3 Cardiopulmonary exercise tests in CF patients classified according to FEV 1

From: Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease

 

All patients (n = 102)

Group 1 (n = 48)

Group 2 (n = 54)

FEV1

 

< 50%

≥ 50%

VO2 peak, mL/kg/min

25 ± 9

20 ± 5d

30 ± 8.5

VO2 peaka

65 ± 21

51 ± 13d

77 ± 20

Borg dyspnea

4.7 ± 1.9

5.6 ± 2b

4.1 ± 1.5

Borg Leg fatigue

4.5 ± 1.8

5.2 ± 1.8b

4.4 ± 1.7

VE peak, L/min

58 ± 22

44 ± 11d

70 ± 21

RR peak, min

41 ± 9

43 ± 9b

39 ± 8

VT/FVC peak, %

48 ± 11

47 ± 13

48.6 ± 8

VE/VO2 peak

41 ± 7

42 ± 7

41 ± 7

VE/VCO2 peak

36 ± 6

37 ± 6

35 ± 5

BR, %

24 ± 20

8 ± 11d

37.5 ± 16

VD/VT peak

0.32 ± 0.11

0.39 ± 0.07d

0.25 ± 0.10

pH peak

7.34 ± 0.04

7.34 ± 0.04

7.35 ± 0.04

PaO2 peak, mm Hg

76 ± 16

63 ± 10d

89 ± 12

PaCO2 peak, mm Hg

40 ± 7

44 ± 6d

36 ± 4

P(A-a)O2 peak, mm Hg

37 ± 13

46 ± 8d

28 ± 10

Lactatemia peak, mmol/L

7 ± 2.6

6 ± 2d

7.9 ± 3

HR peaka

82 ± 10

79 ± 8d

86 ± 9

VO2/HR peaka

79 ± 22

67 ± 16d

90 ± 21

  1. aResults are expressed as mean ± SD percentage of predicted values.
  2. b P < .01 compared with group 2.
  3. c P < .001 compared with group 2.
  4. d P < .0001 compared with group 2.