Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts

BMC Pulmonary Medicine

Table 3 Estimates for the effect of HIV infection on incidence of pulmonary diagnoses

	MACS				WIHS
	Incident rates per 100 person-years		RR (95% CI)	p-value	Incident rates per 100 person-years		RR (95% CI)	p-value
Diagnosis	HIV-infected	HIV-uninfected	HIV-infected vs. HIV-uninfected		HIV-infected	HIV-uninfected	HIV-infected vs. HIV-uninfected
Asthma	0.69	0.62	0.86 (0.35-2.13)	0.75	2.59	3.35	0.87 (0.54-1.41)	0.58
COPD	1.70	0.69	2.21 (1.09-4.50)	0.03	2.13	1.39	1.58 (0.85-2.94)	0.15
Sleep apnea	1.41	1.45	0.92 (0.49-1.73)	0.81	1.12	0.49	2.33 (0.89-6.11)	0.09

Adjusted for age, race, smoking status, and intravenous drug use.
MACS – Multicenter AIDS Cohort Study; WIHS – Women’s Interagency HIV Study; RR– Rate ratio; CI – confidence interval; COPD – chronic obstructive pulmonary disease.

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