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Table 2 Diagnostic validity of the studied parameters for exacerbation of CEP

From: Significance of fractional exhaled nitric oxide in chronic eosinophilic pneumonia: a retrospective cohort study

Variable

AUC

Cutoff value

Sensitivity

Specificity

FeNO level

0.835

66.0 ppb

0.80

0.84

  

50.0 ppb*

0.80

0.77

ΔFeNO

0.918

8.4 ppb

0.83

0.84

  

10.0 ppb**

0.67

0.86

Peripheral eosinophil percentage

0.906

8.4%

0.89

0.79

Peripheral eosinophil count

0.923

451 cells/μL

0.89

0.83

  1. *FeNO level > 50 ppb is indicative of eosinophilic inflammation and corticosteroid responsiveness in symptomatic patients [20].
  2. **ΔFeNO > 10 ppb indicates significant increase in FeNO level [20].