Table 3 Mean ± SD and 95% confidence interval (shown in [ ]) of each pulmonary function variable (absolute and/or percentage predicted values: % predicted) for Huntington’s disease patients (HD) and healthy volunteers (Control)
From: Pulmonary function in patients with Huntington’s Disease
HD | Control | p | |
|---|---|---|---|
MIP (cm H2O) | 72.6 ± 30 [57.7 – 87.6] | 110.1 ± 28.8 [95.8 – 124.4] | 0.000 |
MEP (cm H2O) | 106.2 ± 37 [87.8 – 124.5] | 147.9 ± 38.4 [128.8 – 167.0] | 0.001 |
IC (L) % predicted | 2.7 ± 0.8 [2.3 – 3.1] | 3.2 ± 0.8 [2.8 – 3.6] | 0.063 |
97.0 ± 24.9 [84.7 – 109.4] | 112.3 ± 14.2 [105.2 – 119.4] | 0.015 | |
SVC (L) % predicted | 3.8 ± 1 [3.3 – 4.4] | 4.0 ± 1 [3.6 – 4.6] | 0.237 |
92.2 ± 23.6 [80.4 – 103.9] | 97.4 ± 11.4 [91.7 – 103.0] | 0.203 | |
FVC (L) % predicted | 3.1 ± 1.0 [2.6 – 3.6] | 3.9 ± 1.0 [3.4 – 4.5] | 0.008 |
72.8 ± 17.4 [64.2 – 81.5] | 93.4 ± 13.4 [86.7 – 100.0] | 0.000 | |
FEV1 (L/s) % predicted | 2.6 ± 0.74 [2.2 – 3.0] | 3.0 ± 0.72[2.7 – 3.3] | 0.066 |
80.6 ± 16.8 [72.2 – 89.0] | 92.4 ± 12.6 [86.1 – 98.6] | 0.011 | |
FEV1/FVC | 87 ± 7.4 [83.3 – 90.7] | 77 ± 8.1 [73.3 – 81.4] | 0.000 |
PEF (L/s) % predicted | 5.9 ± 2.0 [4.9 – 6.9] | 7.3 ± 1.9 [6.3 – 8.2] | 0.024 |
64.7 ± 18.4 [55.5 – 73.8] | 81.1 ± 18.9 [71.7 – 90.5] | 0.006 | |
MVV (L/min) % predicted | 103.9 ± 43.0 [82.6 – 125.3] | 142 ± 36.6 [124.7 – 161.1] | 0.003 |
82.6 ± 27.3 [69.0 – 96.1] | 117.1 ± 15.0 [109.5 – 124.5] | 0.000 |