From: Similar matrix alterations in alveolar and small airway walls of COPD patients
Control | GOLD II | GOLD IV | |
---|---|---|---|
Number | 14 | 16 | 19 |
Age (years) | 63 ± 6 | 65 ± 7 | 61 ± 7 |
Sex (M/F) | 9/5 | 13/3 *$ | 12/7 |
Pack-years § | 25 ± 16 | 46 ± 14* | 47 ± 29* |
Smoking status (current/ex) | 4/9 | 11/5 | 0/19*^ |
FEV 1 (%predicted) | 107 ± 15 | 67 ± 9* | 22 ± 4*^ |
FEV 1 /FVC | 80 ± 6 | 59 ± 9* | 26 ± 7*^ |
Tlco (% predicted) # | 95 ± 16 | 77 ± 18* | 35 ± 15*^ |