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Table 1 Clinical characteristics of study subjects

From: Similar matrix alterations in alveolar and small airway walls of COPD patients

 

Control

GOLD II

GOLD IV

Number

14

16

19

Age (years)

63 ± 6

65 ± 7

61 ± 7

Sex (M/F)

9/5

13/3 *$

12/7

Pack-years §

25 ± 16

46 ± 14*

47 ± 29*

Smoking status (current/ex)

4/9

11/5

0/19*^

FEV 1 (%predicted)

107 ± 15

67 ± 9*

22 ± 4*^

FEV 1 /FVC

80 ± 6

59 ± 9*

26 ± 7*^

Tlco (% predicted) #

95 ± 16

77 ± 18*

35 ± 15*^

  1. Data are displayed as mean ± SD or ratio, * means p < 0.05 compared to controls, $ means significantly different compared GOLD IV. ^ means significant compared to GOLD II. § Values from 3 controls, 4 COPD GOLD II and 2 GOLD IV patients are missing. # Values from 2 controls, 1 COPD GOLD II and 9 GOLD IV patients are missing. FEV1 (%predicted) and FEV1/FVC are measured post-broncholdilation.