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Figure 5 | BMC Pulmonary Medicine

Figure 5

From: Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)

Figure 5

Heterogeneous deposition of elastic fibers in the lungs of patients with idiopathic pleuroparenchymal fibroelastosis (IPPFE). Lung specimens were obtained from the both upper lobe and lower lobes in five of the six patients with IPPFE. Elastic fiber scores (EF scores) in each lobe are shown (A). EF scores in lower lobes were significantly lower than those in the upper lobes in patients with IPPFE (median, 24.2% [range 20.3-26.5%] vs. 32.4% [range 24.9-39.6%], p = 0.048). Values in the same patient are connected by solid lines. The horizontal bar represents the median. Even in the lower lobes, the EF scores in patients with IPPFE were still higher than those in patients with IPF (C, p < 0.0001) as well as in the upper lobes (B, p = 0.0007).

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