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Table 1 Comparison between idiopathic pleuroparenchymal fibroelastosis (IPPFE) and idiopathic pulmonary fibrosis (IPF): clinical characteristics

From: Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)

  IPPFE (n = 6) IPF (n = 28) p value
Sex, male/female 5/1 26/2 0.452*
Age at biopsy, yr 69.2 ± 3.9 61.4 ± 9.9 0.072
Smoking history, current/ex/never 0/3/3 13/13/2 0.011*
Pack-year of smoking 29.3 ± 33.1 66.8 ± 97.4 0.363
Detection by medical check-up, n (%) 3 (50) 21 (75.0) 0.328*
Respiratory symptoms at biopsy, n (%) 6 (100) 19 (67.9) 0.162*
Body mass index, kg/m2 17.9 ± 0.9 24.3 ± 2.8 <0.0001
Clubbing of finger, n (%) 1 (16.7) 6 (21.4) 0.999*
Fine crackles, n (%) 3 (50) 27 (96.4) 0.012*
Pneumothorax, n (%) 4 (66.7) 1 (3.6) 0.002*
Acute exacerbation, n (%) 1 (16.7) 6 (21.4) 0.999*
Therapeutic intervention, n (%) 4 (66.7) 15 (53.6) 0.672*
Period from detection of IP until acquisition of lung specimens 73.3 ± 46.1 29.7 ± 34.3 0.012
Observation period, mo 39.8 ± 29.2 67.8 ± 46.7 0.206
Death, n (%) 3 (50.0) 12 (42.9) 0.999*
  1. Data are presented as n, mean ± SD or n (%).
  2. Data were analyzed with Student’s t-test or *Fisher’s exact probability test.
  3. Abbreviations: IPPFE idiopathic pleuroparenchymal fibroelastosis, IPF idiopathic pulmonary fibrosis, IP interstitial pneumonia.