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Table 3 Comparison between idiopathic pleuroparenchymal fibroelastosis (IPPFE) and idiopathic pulmonary fibrosis (IPF): findings on high resolution computed tomography (HRCT) and lung specimens

From: Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)

  IPPFE (n = 6) IPF (n = 28) p value
Findings on HRCT    
 Extent score, 0-25 9.8 ± 2.6 8.8 ± 3.7 0.366
 Upper lobe predominant distribution, n (%) 6 (100) 0 (0) <0.0001*
 Reticulation score, 0-3 1.3 ± 0.5 1.8 ± 0.7 0.161
 Glass score, 0-3 1.5 ± 0.8 1.7 ± 0.7 0.429
 Consolidation score, 0-3 1.7 ± 0.8 0.3 ± 0.5 0.004
 Existence of honeycombing, n (%) 0 (0) 10 (35.7) 0.148*
 Emphysema score, 0-3 0 0.7 ± 0.9 0.078
 Pleural thickening, n (%) 6 (100) 2 (7.1) <0.0001*
Findings on surgical lung biopsy specimens    
 Collagen deposition score, 0-3 2.0 ± 0 2.4 ± 0.8 0.175
 Existence of microscopic honeycombing, n (%) 1 (16.7) 17 (60.7) 0.078*
 Organizing pneumonia score, 0-3 1.8 ± 0.4 0.6 ± 0.7 0.003
 Cellularity score in interstitium, 0-3 1.5 ± 0.5 1.3 ± 0.6 0.456
 Lymphoid hyperplasia, n (%) 0 (0) 0 (0) NA.
 Pleural fibrosis, pleuritis, n (%) 5 (83.3) 0 (0) <0.0001*
  1. Data are presented as mean ± SD or, n (%).
  2. Data are analysed with Mann-Whitney’s U-test or *Fisher’s exact probability test.
  3. HRCT high resolution computed tomography, NA not applicable.