Table 1 Baseline characteristics of 342 COPD patients recruited at their first hospitalisation for a COPD exacerbation
All COPD patients n = 342* | Undiagnosed COPD n = 117 (34%) | Diagnosed COPD n = 225 (66%) | p-value† | |
|---|---|---|---|---|
Age (years), m (SD) | 67 (9) | 66 (9) | 68 (8) | 0.03 |
Males, n (%) | 318 (93) | 107 (92) | 211(94) | 0.43 |
Married, n (%) | 274 (80) | 90 (77) | 184 (82) | 0.29 |
Less than primary education, n (%) | 142 (42) | 46 (39) | 96 (43) | 0.55 |
Low socioeconomic status (IV-V), n (%) | 259 (82) | 90 (81) | 169 (82) | 0.83 |
Current workers, n (%) | 61 (18) | 30 (26) | 31 (14) | <0.01 |
Smoking status: current, n (%) | 150 (44) | 69 (59) | 81 (36) | <0.01 |
Pack-years, m (SD) | 69 (40) | 67 (38) | 70 (41) | 0.55 |
Physical activity (hours/week), m (SD) | 33.5 (23.8) | 39.5 (23.4) | 30.4 (23.5) | 0.01 |
≥2 comorbidities (Charlson index), n (%) | 172 (50) | 47 (40) | 125 (56) | <0.01 |
Severity of COPD (ERS/ATS), n (%) | ||||
Mild (FEV1 ≥ 80%) | 19 (5) | 14 (12) | 5 (2) | <0.01 |
Moderate (FEV1 ≥ 50%, <80%) | 164 (48) | 65 (56) | 99 (44) | |
Severe (FEV1 ≥ 30%, <50%) | 132 (39) | 33 (28) | 99 (44) | |
Very severe (FEV1 < 30%) | 27 (8) | 5 (4) | 22 (10) | |
FEV1 post-bronchodilator (% pred), m (SD) | 52 (16) | 59 (16) | 49 (15) | <0.01 |
DLCO (% pred.), m (SD) | 65 (21) | 67 (21) | 64 (21) | 0.23 |
RV/TLC (%), m (SD) | 56 (10) | 52 (10) | 58 (9) | <0.01 |
PaO2 (mmHg), m (SD) | 74 (11) | 75 (10) | 74 (11) | 0.28 |
PaCO2 (mmHg), m (SD) | 41.8 (5.3) | 42.2 (5.2) | 41.6 (5.4) | 0.37 |
6MWD (m), median (P25-P75) | 437 (390–500) | 440 (396–502) | 437 (373–498) | 0.25 |
Dyspnoea score (mMRC, score 0–4), m (SD) | 2.40 (1.06) | 2.06 (1.09) | 2.59 (0.99) | <0.01 |
BMI (Kg/m2), m (SD) | 28.2 (4.7) | 28.8 (4.7) | 27.9 (4.6) | 0.08 |
FFMI (Kg/m2), m (SD) | 19.7 (3.1) | 19.9 (3.0) | 19.5 (3.1) | 0.21 |
SGRQ total score (0 no health impairment to 100 maximum impairment), m (SD) | 37 (18) | 29 (16) | 40 (18) | <0.01 |
SGRQ symptoms score, m (SD) | 48 (18) | 45 (16) | 50 (18) | <0.01 |