Skip to main content

Table 1 Subject Demographic and Clinical Characteristics by 30-Day Mortality*

From: The impact of prior outpatient ACE inhibitor use on 30-day mortality for patients hospitalized with community-acquired pneumonia

  30-Day Mortality  
Variable Alive (n = 714) Dead (n = 72) p-value
Age, years +/- standard deviation 60.2+/-16.4 62.9 +/-16.4 0.09
Men 561 (79) 60 (83) 0.3
Nursing home resident 41 (6) 13 (18) <0.001
Emergency department admission 598 (84) 58 (81) 0.5
Admitted to intensive care ≤ 24 hours 118 (17) 36 (50) <0.001
Preexisting Comorbid Conditions
   Congestive heart failure 105 (15) 18 (25) 0.02
   Chronic pulmonary disease 195 (27) 23 (31) 0.4
   History of stroke 93 (13) 12 (17) 0.4
   Chronic liver disease 83 (12) 11 (15) 0.4
   History of malignancy 58 (8) 20 (28) <0.001
   Renal insufficiency 74 (10) 13 (18) 0.05
History, Physical, Laboratory, and Radiographic Data
   Altered mental status 68(10) 17(24) <0.001
   Respiratory rate > 30 per minute 71 (10) 11 (15) 0.2
   Systolic blood pressure < 90 mmHg 16 (2) 5 (7) 0.02
   Heart rate > 125 per minute 86 (12) 19 (26) 0.001
   Temperature < 95° or > 104° 19 (3) 2 (3) 0.9
   Arterial pH < 7.35 37 (5) 12 (17) <0.001
   Arterial oxygenation < 90% 149 (21) 27 (38) 0.001
   Hematocrit < 30% 64 (9) 8 (11) 0.5
   Blood urea nitrogen > 30 mg/dL 135 (19) 33 (46) <0.001
   Serum glucose > 250 mg/dL 71 (10) 5 (7) 0.4
   Serum sodium < 130 meq/L 98 (14) 18 (25) 0.01
   Pleural effusion 160 (11) 29 (35) 0.001
Pneumonia Severity Index
   Class I-III 393 (54) 16 (22)  
   Class IV 240 (34) 26 (36)  
   Class V 82 (12) 30 (42) <0.001
Processes of Care
   Initial antibiotics within 4 hours 201 (28) 22 (31) 0.7
   Initial antibiotics within 8 hours 358 (50) 36 (50) 1.0
   Blood cultures prior to antibiotics 540 (76) 55 (76) 0.9
   Oxygenation assessed ≤ 24 hours 538 (75) 65 (90) 0.004
   Guideline-concordant antibiotics 574 (80) 51 (71) 0.05
Outpatient Medications
   ACE inhibitor 183 (25) 11 (15) 0.05
  1. * Data are presented as number (%) or mean +/-standard deviation