ACE Inhibitor Use | |||
---|---|---|---|
Variable | Not on ACE inhibitor (n= 593) | On ACE inhibitor (n=194) | p-value |
Age, years +/- standard deviation | 58.2 +/-16.9 | 67.1+/-13.6 | <0.001 |
Men | 467 (79) | 154(80) | 0.8 |
Nursing home resident | 43(7) | 11(6) | 0.4 |
Emergency department admission | 498(84) | 158(81) | 0.38 |
Admitted to intensive care ≤ 24 hours | 116(20) | 38(20) | 1.0 |
Preexisting Comorbid Conditions | |||
Diabetes Mellitus | 138(23) | 92(47) | <0.001 |
Coronary artery disease | 132(22) | 98(51) | <0.001 |
Chronic pulmonary disease | 151(25) | 67(35) | <0.001 |
Current tobacco use | 200(31) | 35(18) | <0.001 |
Congestive heart failure | 59(10) | 64(33) | <0.001 |
History of stroke | 67(11) | 38(20) | 0.003 |
Chronic liver disease | 82(14) | 12(6) | 0.004 |
History of malignancy | 57(10) | 21(11) | 0.6 |
Renal insufficiency | 54(9) | 33(17) | 0.002 |
History, Physical, Laboratory, and Radiographic Data | |||
Altered mental status | 62(10) | 23(12) | 0.6 |
Respiratory rate > 30 per minute | 67(11) | 15(8) | 0.16 |
Systolic blood pressure < 90 mmHg | 17(3) | 4(2) | 0.5 |
Heart rate > 125 per minute | 87(15) | 18(9) | 0.06 |
Temperature < 95° or > 104° | 18(3) | 3(2) | 0.26 |
Arterial pH < 7.35 | 33(6) | 16(8) | 0.18 |
Arterial oxygenation < 90% | 128(22) | 48(25) | 0.4 |
Hematocrit < 30% | 59(10) | 13(7) | 0.17 |
Blood urea nitrogen > 30 mg/dL | 110(19) | 58(30) | <0.001 |
Serum glucose > 250 mg/dL | 50(8) | 26(13) | 0.04 |
Serum sodium < 130 meq/L | 95(16) | 21(11) | 0.08 |
Pleural effusion | 141(24) | 48(25) | 0.8 |
Pneumonia Severity Index | |||
Class I-III | 332(56) | 77(40) | |
Class IV | 187(32) | 79(41) | |
Class V | 74(12) | 38(20) | <0.001 |