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Table 2 Use versus non-use of ACE inhibitors by demographic and clinical characteristics*

From: The impact of prior outpatient ACE inhibitor use on 30-day mortality for patients hospitalized with community-acquired pneumonia

  ACE Inhibitor Use  
Variable Not on ACE inhibitor
(n= 593)
On ACE inhibitor
(n=194)
p-value
Age, years +/- standard deviation 58.2 +/-16.9 67.1+/-13.6 <0.001
Men 467 (79) 154(80) 0.8
Nursing home resident 43(7) 11(6) 0.4
Emergency department admission 498(84) 158(81) 0.38
Admitted to intensive care ≤ 24 hours 116(20) 38(20) 1.0
Preexisting Comorbid Conditions
   Diabetes Mellitus 138(23) 92(47) <0.001
   Coronary artery disease 132(22) 98(51) <0.001
   Chronic pulmonary disease 151(25) 67(35) <0.001
   Current tobacco use 200(31) 35(18) <0.001
   Congestive heart failure 59(10) 64(33) <0.001
   History of stroke 67(11) 38(20) 0.003
   Chronic liver disease 82(14) 12(6) 0.004
   History of malignancy 57(10) 21(11) 0.6
   Renal insufficiency 54(9) 33(17) 0.002
History, Physical, Laboratory, and Radiographic Data
   Altered mental status 62(10) 23(12) 0.6
   Respiratory rate > 30 per minute 67(11) 15(8) 0.16
   Systolic blood pressure < 90 mmHg 17(3) 4(2) 0.5
   Heart rate > 125 per minute 87(15) 18(9) 0.06
   Temperature < 95° or > 104° 18(3) 3(2) 0.26
   Arterial pH < 7.35 33(6) 16(8) 0.18
   Arterial oxygenation < 90% 128(22) 48(25) 0.4
   Hematocrit < 30% 59(10) 13(7) 0.17
   Blood urea nitrogen > 30 mg/dL 110(19) 58(30) <0.001
   Serum glucose > 250 mg/dL 50(8) 26(13) 0.04
   Serum sodium < 130 meq/L 95(16) 21(11) 0.08
   Pleural effusion 141(24) 48(25) 0.8
Pneumonia Severity Index
   Class I-III 332(56) 77(40)  
   Class IV 187(32) 79(41)  
   Class V 74(12) 38(20) <0.001
  1. * Data are presented as number (%) or mean +/-standard deviation