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Table 4 Multivariate Coefficients (sd) for Rate of loss of Actual FEV1 (after allowance for regression to the mean)

From: The Darlington and Northallerton Long Term Asthma Study: pulmonary function

  

Age Excluded

Age Included

  

Coefficient

p

Coefficient

p

Gender (male v female)

5.5 (4.8)

0.25

5.7 (4.7)

0.23

Asthma since childhood

13.5 + (5.1)

0.008

4.9+ (5.8)

0.40

Social Classes 1 & 2 (v. classes 4 & 5)

4.8 (5.4)

0.65

1.8 (5.4)

0.88

Social Class 3 (v. classes 4 & 5)

1.1 (5.1)

 

0.6+ (5.0)

 

Amount smoked (per 10 pack years)

1.8 (1.2)

0.13

1.0 (1.2)

0.39

Best PEF(per 10% deficit)

1.2+ (1.2)

0.33

0.9+ (1.2)

0.41

Actual/Best PEF(10% deficit)

12.0 + (1.6)

<0.0001

13.2 + (1.6)

<0.0001

Age at entry (per decade) (difference from age 50)

Linear

  

3.5+ (3.1)

 
 

quadratic

  

4.9+ (0.9)

 
 

cubic

  

1.2 (0.6)

0.02

Duration of asthma at entry (per decade) (difference from duration 20 yrs)

Linear

1.3 (2.8)

 

2.0+ (2.4)

 
 

quadratic

3.2 (1.5)

 

0.9 (0.5)

 
 

cubic

0.85 + (0.38)

0.03

2.5+ (0.39)

0.52

  1. (+) Indicates relative gain in function