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Table 3 Total and differential cell counts at baseline and the standard mean difference (SMD) in cell counts between intervention group and placebo group after treatment.

From: Effects of inhaled corticosteroids on sputum cell counts in stable chronic obstructive pulmonary disease: a systematic review and a meta-analysis

Source

Total cells

Neutrophils

Lymphocytes

Eosinophils

Macrophages

 

Number (× 104/mL)

SMD (95% CI)

Number (× 104/mL)

SMD (95% CI)

Number (× 104/mL)

SMD (95% CI)

Number (× 104/mL)

SMD (95% CI)

Number (× 104/mL)

SMD (95% CI)

Yildiz [22]

350.0

-0.6 (-1.6 to 0.4)

260.0

-2.2 (-3.4 to -1.0)

3.5

-0.5 (-1.4 to 0.5)

7.0

-1.1 (-2.1 to -0.1)

80.0

0.2 (-0.5 to 0.9)

Confalonieri [20]

219.0

-0.4 (-1.1 to 0.3)

158.8

-3.4 (-4.5 to -2.3)

6.6

-0.5 (-1.2 to 0.2)

6.2

-0.6 (-1.3 to 0.1)

45.0

-0.3 (-0.9 to 0.3)

Mirici [21]

196.5

-1.0 (-1.7 to -0.3)

146.5

-7.5 (-9.3 to -5.6)

1.6

-0.7 (-1.4 to -0.1)

1.6

0.2 (-0.4 to 0.8)

38.2

0.5 (-0.5 to 1.5)

Sugiura [7]

165.7

0.2 (-0.8 to 1.2)

102.9

0.1 (-0.9 to 1.1)

6.1

0.04 (-0.9 to 1.0)

4.5

-0.2 (-1.2 to 0.8)

52.0

-0.3 (-1.1 to 0.5)

Culpitt [19]

165.0

-0.3 (-1.1 to 0.5)

145.0

-0.4 (-1.2 to 0.4)

NR

NR

NR

NR

25.0

-0.2 (-0.9 to 0.6)

Keatings [18]

6.3*

-0.1 (-0.9 to 0.7)

4.3*

-0.4 (-1.1 to 0.4)

6.0*

0.0 (-0.7 to 0.8)

0.2*

-0.2 (-1.0 to 0.6)

1.8*

0.2 (-0.7 to 1.2)

Pooled Summary

 

-0.4 (-0.8 to -0.1)

 

-2.2 (-3.8 to -0.5)

 

-0.4 (-0.7 to -0.1)

 

-0.3 (-0.6 to 0.1)

 

-0.02 (-0.3 to 0.3)

  1. * cell count/ml
  2. Abbreviations: NR, not reported/not calculable.