Table 2 Patterns of inflammatory markers within clinical diagnosis groups. Results are expressed in means (SD).
From: Patterns of inflammation and the use of reversibility testing in smokers with airway complaints
Compartment | Inflammatory markers | COPD | Asthma | CB | HS |
|---|---|---|---|---|---|
Sputum cell counts | Volume (ml) | 6.7 (0.86) | 6.9 (0.95) | 6.8 (0.93) | 3.4 (0.42) |
Total counts (106 cells/ml) | 4.3 (0.80) | 2.3 (0.91) | 2.0 (0.5) | 4.0 (0.99) | |
Neutrophils (%) | 81.3* (12.2) | 49.0* (25.2) | 56.6 (23.2) | 62.4 (16.5) | |
Eosinophils (%) | 1.8 (3.7) | 20.2* (30.0) | 1.3 (1.5) | 0.8 (1.1) | |
Lymphocytes (%) | 0.7 (1.2) | 1.8 (2.7) | 3.4* (3.4) | 0.9 (0.8) | |
Macrophages (%) | 16.8* (10.5) | 29.1 (24.0) | 38.6 (21.9) | 35.9 (15.6) | |
Sputum mediators | sTNF-R55 (pg/ml) | 658.2* (785.0) | 64.4 (14.6) | 97.2 (72.7) | 169.2 (135.5) |
sTNF R-75 (pg/ml) | 222.7* (289.3) | 64.3 (53.9) | 87.6 (68.1) | 84.6 (68.8) | |
LBP (ng/ml) | 10.1 (11.2) | 9.3 (6.3) | 7.9 (8.3) | 5.3 (5.7) | |
IL-8 (ng/ml) | 5.5* (3.9) | 2.6 (3.2) | 2.7 (1.7) | 2.4 (1.5) | |
Plasma mediators | sTNF-R55 (ng/ml) | 2.0* (0.5) | 1.6 (0.4) | 1.5* (0.3) | 1.8 (0.4) |
sTNF-R75 (ng/ml) | 2.0* (0.4) | 1.7 (0.5) | 1.4* (0.3) | 1.5 (0.4) | |
LBP (μg/ml) | 28.2* (11.2) | 20.0 (4.7) | 22.8 (6.5) | 17.6* (4.5) | |
IL-8 (pg/ml) | 7.7* (1.3) | 7.1 (0.3) | 7.2 (0.6) | 7 (0.0) |