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Table 3 Univariate and multivariate relations between inflammatory markers in sputum and plasma and clinical diagnosis groups.

From: Patterns of inflammation and the use of reversibility testing in smokers with airway complaints

Compartment

Inflammatory markers

COPD

Asthma

CB

HS

Sputum cell counts

Neutrophils (%)

+

-

  
 

Eosinophils (%)

 

+/++

  
 

Lymphocytes (%)

  

+/++

 
 

Macrophages (%)

-

   

Sputum mediators

sTNF-R55 (pg/ml)

+/++

   
 

sTNF-R75 (pg/ml)

+

   
 

LBP (ng/ml)

    
 

IL-8 (ng/ml)

+

   

Plasma mediators

sTNF-R55 (ng/ml)

+

 

-

 
 

sTNF-R75 (ng/ml)

+

 

-

 
 

LBP (μg/ml)

+/++

  

-/–

 

IL-8 (pg/ml)

+

   
  1. (+ indicates positive univariate significance; - indicates significant negative univariate relation; ++ indicates positive multivariate significance; -- indicates negative multivariate significance) CB = chronic bronchitis; HS = healthy smokers