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Table 3 Univariate and multivariate relations between inflammatory markers in sputum and plasma and clinical diagnosis groups.

From: Patterns of inflammation and the use of reversibility testing in smokers with airway complaints

Compartment Inflammatory markers COPD Asthma CB HS
Sputum cell counts Neutrophils (%) + -   
  Eosinophils (%)   +/++   
  Lymphocytes (%)    +/++  
  Macrophages (%) -    
Sputum mediators sTNF-R55 (pg/ml) +/++    
  sTNF-R75 (pg/ml) +    
  LBP (ng/ml)     
  IL-8 (ng/ml) +    
Plasma mediators sTNF-R55 (ng/ml) +   -  
  sTNF-R75 (ng/ml) +   -  
  LBP (μg/ml) +/++    -/–
  IL-8 (pg/ml) +    
  1. (+ indicates positive univariate significance; - indicates significant negative univariate relation; ++ indicates positive multivariate significance; -- indicates negative multivariate significance) CB = chronic bronchitis; HS = healthy smokers