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Table 3 Diagnostic performance of baseline characteristics of COPD patients in distinguishing those with an adverse reaction during SI.

From: Dyspnea assessment and adverse events during sputum induction in COPD

 

Cut-off value

Sensitivity

Specificity

Positive predictive value

Negative predictive value

A 2 ge

>70

65

52

42

77

FEV 1 , (% pred)

<40

83

64

47

91

ΔSpO 2 (%)

≤91

74

78

54

88

MRC score

> 2

52

86

56

82

Borg

>4

66

55

44

80

6MWT distance (m)

≤155

52

98

90

84

ΔBorg 6MWT

>2

82

55

33

73

  1. FEV1 = post-bronchodilation forced expiratory volume in one second; ΔSpO2 = oxygen saturation average changes; MRC = Medical Research Council; 6MWT = six minutes walking test; ΔBorg6MWT = Borg dyspnea score change after 6MWT.