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Table 3 Diagnostic performance of baseline characteristics of COPD patients in distinguishing those with an adverse reaction during SI.

From: Dyspnea assessment and adverse events during sputum induction in COPD

  Cut-off value Sensitivity Specificity Positive predictive value Negative predictive value
A 2 ge >70 65 52 42 77
FEV 1 , (% pred) <40 83 64 47 91
ΔSpO 2 (%) ≤91 74 78 54 88
MRC score > 2 52 86 56 82
Borg >4 66 55 44 80
6MWT distance (m) ≤155 52 98 90 84
ΔBorg 6MWT >2 82 55 33 73
  1. FEV1 = post-bronchodilation forced expiratory volume in one second; ΔSpO2 = oxygen saturation average changes; MRC = Medical Research Council; 6MWT = six minutes walking test; ΔBorg6MWT = Borg dyspnea score change after 6MWT.