Table 1 Variables to be collected in the cross-sectional and nested case-control studies
Cross-sectional | Case-control | |
|---|---|---|
Allergy questions | ||
Core asthma symptom questions (ISAAC phase II) | X | X |
Core rhinitis symptom questions (ISAAC phase II) | X | X |
Core eczema symptom questions (ISAAC phase II) | X | X |
Supplementary asthma questions (ISAAC phase II) | X | |
Asthma management questions (ISAAC phase II) | X | |
Rhinitis management questions (ISAAC phase II) | X | |
Eczema management questions (ISAAC phase II) | X | |
Knowledge attitude practice questions (KAP) | X | |
Demographic and socio-economic | ||
Sex | X | X |
Age | X | X |
Race | X | X |
On socio-economic level: | ||
parental schooling | X | |
parental occupation | X | X |
domestic goods | X | X |
monthly income | X | X |
Environmental factors | ||
Sanitation and water supply | X | X |
Does the house have electricity? | X | X |
Pets | ||
Has the child ever had a cat or dog living in the house? | X | |
Does the child have a cat or dog living in the house currently? | X | X |
Presence of animals outside household | X | X |
Indoor smoking | X | X |
Exposure to a farming environment | X | X |
Housing (e.g. construction, number of rooms) | X | X |
Presence of allergens in dust (mites and cockroach) | X | |
Presence of endotoxin in the house | X | |
Cooking materials | X | X |
Maternal and family related factors | ||
Maternal smoking during pregnancy | X | |
Asthma and other allergic diseases in the family | X | |
Breast-feeding duration | X | |
Vaccination (BCG, DTP, measles) | X | |
Whether attended day care (and for what period) | X | |
Number of people who live in each household | X | X |
Number of siblings or children in the household | X | X |
Birth order | X | X |
Diet | ||
Food frequency questionnaire | X | X |
Consumption of unpasteurized milk | X | |
Migration | ||
Place of birth of child | X | |
Place of birth of father | X | |
Place of birth of mother | X | |
Was the father brought up in an urban or rural area? | X | |
Was the mother brought up in an urban or rural area? | X | |
Period of time and places living outside place of birth during first 5 years of life | X | |
Details of relatives living in the city of Esmeraldas | X | |
Exercise/sedentarism | ||
Number of hours of television watched daily | X | X |
Frequency of vigorous exercise | X | X |
Nutritional assessment | ||
Hemoglobin | X | X |
Height | X | X |
Weight | X | X |
Mid-upper arm circumference | X | |
Triceps skin fold thickness | X | |
Specific Infections | ||
Intestinal helminth and protozoal infections (stool examinations) | X | X |
A. lumbricoides IgE | X | |
IgG for Toxoplasma. Gondii, Helicobacter pylori and viral infections | X | |
Exercise test for exercise-induced bronchospasm | X | |
Atopy | ||
Skin prick test | X | X |
Total and specific IgE titres to house dust mite and American cockroach | X | |
Immunoregulatory cytokines | ||
IL-10, IL-13, IFN-γ | X |