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Table 2 Between Cell Culture Condition Comparisons of TH2 Cell Positivity for IL-4 and IFN-γ

From: NKG2A inhibits TH2 cell effector function in vitro

Condition   IL-4 Positive (%) Fold IL-4 MFI IFNγ Positive (%) Fold IFNγ MFI
Positive Control (CD3/CD28) Mean 25.5% 22.47 7.7% 7.43
  SEM 6.8% 12.26 1.3% 1.42
  p-value (Negative Control) 0.003 0.03 0.05 0.05
  p-value (Isotype Control) 0.11 0.18 0.35 0.24
Anti-NKG2A Antibody (CD3/CD28 + anti-NKG2A) Mean 9.3% 4.39 5.5% 5.29
  SEM 4.8% 1.81 1.3% 1.50
  p-value (Positive Control) 0.001 0.01 0.04 0.01
  p-value (Isotype Control) 0.005 0.066 0.427 0.234
Isotype Control (CD3/CD28 + IgG2a) Mean 23.7% 7.81 4.9% 6.50
  SEM 1.0% 0.72 2.7% 0.43
  p-value - - - -
Negative Control (Culture Medium Alone) Mean 6.7% 2.76 4.8% 4.83
  SEM 4.6% 0.63 0.8% 1.60
  p-value - - - -
  1. p ≤ 0.05 in bold.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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