Skip to main content

Table 1 Baseline values for all patients (n = 9)

From: Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease

Baseline characteristics  
   Gender (female/male) 3/6
   Age (years)* 72 (51–86)
   Body-mass index (kg/m 2)* 25.9 (24.7–33.7)
   Smoking (pack years)* 30 (25–50)
   Duration of COPD (years)* 2.0 (1–4)
   Number of AECOPD in previous year* 1 (1–2)
   Duration of AECOPD (days) 4 (4–7)
   Dyspnea (%) 9 (100%)
   Cough (%) 9 (100%)
   Increased sputum production (%) 9 (100%)
   Discoloured sputum (%) 7 (78%)
   Fever (%) 7 (78%)
   Maintenance therapy at admission (%)  
β2-agonist and/or anticholinergic 7 (78%)
Inhaled corticosteroids 4 (44%)
Oral corticosteroids 0 (0%)
Theophyllin 0 (0%)
Long-term oxygen therapy 1 (11%)
   Severity of AECOPD – Anthonisen's criteria [8] (%)  
1 0 (0%)
2 2 (22%)
3 7 (78%)
   Heart rate* (beats/min) 84 (70–101)
   Blood pressure* (mmHg)  
   Systolic 143 (120–150)
   Diastolic 80 (69–85)
   Respiratory rate* 16 (12–25)
Laboratory findings:  
   Leukocytes total* 9.3 (7.7–10.1)
   CRP (mg/dl)* 19 (6–61)
   Cortisol basal (nmol/l)** 439 (392–462)
   Cortisol after 1 μg ACTH (nmol/l)** 712 (608–730)
   Basal ACTH (ng/l)** 9.2 (5.1–11.5)
  1. * median, interquartile range;