Figure 2From: Surfactant replacement and open lung concept – Comparison of two treatment strategies in an experimental model of neonatal ARDS Ventilation efficiency index (VEI). Left panel. Time course of ventilation efficiency index (VEI) over the observation period. Induction of lung injury by repetitive lavage procedures (T = 0) is followed by open lung concept positive pressure ventilation (PPVOLC; n = 5) or surfactant treatment under conventional positive pressure ventilation with a natural bovine surfactant (Alveofact®; nat SF; n = 4) or a modified monomeric surfactant protein B surfactant (mon SP-B; n = 4). Right panel. Difference of VEI over the study period (T5-T0). Study groups: open lung concept positive pressure ventilation (PPVOLC; n = 5); surfactant treatment under conventional positive pressure ventilation with a modified monomeric surfactant protein B surfactant (mon SP-B; n = 4) or a natural bovine surfactant (Alveofact®; nat SF; n = 4). Results are given as mean and standard deviation. * p < 0.05 vs PPVOLC.Back to article page