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Figure 1 | BMC Pulmonary Medicine

Figure 1

From: Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice

Figure 1

A. Immunohistochemical reaction for neutrophil myeloperoxidase on a lung of a C57Bl/6J mouse after a 6 month cigarette smoke exposure. B. Neutrophil volume density in the lung of C57BL76J mice exposed either to room air or to cigarette smoke for 6 months and treated or not with roflumilast at 2 doses. Air = air exposure; CS = cigarette smoke exposure; R1 = treated with roflumilast at the dose 1 mg/kg po; R5 = treated with roflumilast at the dose 5 mg/kg po; N = 5 in all groups; * = p < 0.01 versus air exposed, ++ = < 0.01 versus smoke exposed. Scale Bar = 40 μm.

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