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Table 1 Patient characteristics

From: High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis

 

COP

Idiopathic UIP

Idiopathic cellular and fibrosing NSIP

Idiopathic fibrosing NSIP

p value

Age (years)

68 (43–79)

64 (34–75)

71 (56–75)

50 (28–67)

ns

Sex (male/female)

5/2

11/5

2/5

4/4

ns

Smoking (none/ex/smoker)

3/3/1

6/4/6

5/1/1

4/2/2

ns

Spirometry:

     

   VC (L)

2.79 (1.86–4.21)

2.73 (1.14–3.60)

2.44 (1.28–3.32)

2.72 (1.73–3.39)

ns

   predicted VC (%)

101.6 (53.0–111.2)

82.9 (43.3–112.5)

76.6 (56.8–108.1)

94.7 (66.9–101.5)

ns

   FEV1 (L)

2.17 (1.39–2.81)

2.18 (1.04–2.67)

1.73 (0.99–2.53)

2.2 (1.26–2.98)

ns

   predicted FEV (%)

77.6 (69.8–80.0)

83.3 (69.4–98.2)

85.0 (60.1–96.2)

80.9 (66.5–89.5)

ns

Gas exchange:

     

   DLco (ml/min/mmHg)

10.28 (6.39–17.81)

8.59 (2.32–14.65)

9.94 (7.24–14.60)

12.18 (7.77–19.85)

ns

   predicted DLco (%)

58.6 (49.3–105.1)

46.3 (14.2–97.3)

67.5 (44.7–109.3)

53.1 (46.8–71.9)

ns

Lung volume:

     

   predicted TLC (%)

88.3 (49.0–98.4)

69.3 (32.6–78.7)

68.3 (66.3–104.2)

74.8 (62.9–96.6)

ns

   TLC (L)

3.41 (2.32–5.81)

3.86 (1.27–4.78)

4.24 (2.27–8.80)

3.15 (2.44–4.46)

ns

Arterial blood gases:

     

   PaO2 (mmHg)

76.2 (61.3–83.1)

80.7 (47.2–103.3)

74.2 (70.0–86.4)

85.4 (77.5–92.9)

ns

  1. Data are median (range). ns = not significant
  2. COP = cryptogenic organizing pneumonia; DLco = diffusing capacity for carbon monoxide; FEV = forced expiratory volume; NSIP = nonspecific interstitial pneumonia; TLC = total lung capacity; UIP = usual interstitial pneumonia; VC = vital capacity.