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Table 1 Patient characteristics

From: High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis

  COP Idiopathic UIP Idiopathic cellular and fibrosing NSIP Idiopathic fibrosing NSIP p value
Age (years) 68 (43–79) 64 (34–75) 71 (56–75) 50 (28–67) ns
Sex (male/female) 5/2 11/5 2/5 4/4 ns
Smoking (none/ex/smoker) 3/3/1 6/4/6 5/1/1 4/2/2 ns
Spirometry:      
   VC (L) 2.79 (1.86–4.21) 2.73 (1.14–3.60) 2.44 (1.28–3.32) 2.72 (1.73–3.39) ns
   predicted VC (%) 101.6 (53.0–111.2) 82.9 (43.3–112.5) 76.6 (56.8–108.1) 94.7 (66.9–101.5) ns
   FEV1 (L) 2.17 (1.39–2.81) 2.18 (1.04–2.67) 1.73 (0.99–2.53) 2.2 (1.26–2.98) ns
   predicted FEV (%) 77.6 (69.8–80.0) 83.3 (69.4–98.2) 85.0 (60.1–96.2) 80.9 (66.5–89.5) ns
Gas exchange:      
   DLco (ml/min/mmHg) 10.28 (6.39–17.81) 8.59 (2.32–14.65) 9.94 (7.24–14.60) 12.18 (7.77–19.85) ns
   predicted DLco (%) 58.6 (49.3–105.1) 46.3 (14.2–97.3) 67.5 (44.7–109.3) 53.1 (46.8–71.9) ns
Lung volume:      
   predicted TLC (%) 88.3 (49.0–98.4) 69.3 (32.6–78.7) 68.3 (66.3–104.2) 74.8 (62.9–96.6) ns
   TLC (L) 3.41 (2.32–5.81) 3.86 (1.27–4.78) 4.24 (2.27–8.80) 3.15 (2.44–4.46) ns
Arterial blood gases:      
   PaO2 (mmHg) 76.2 (61.3–83.1) 80.7 (47.2–103.3) 74.2 (70.0–86.4) 85.4 (77.5–92.9) ns
  1. Data are median (range). ns = not significant
  2. COP = cryptogenic organizing pneumonia; DLco = diffusing capacity for carbon monoxide; FEV = forced expiratory volume; NSIP = nonspecific interstitial pneumonia; TLC = total lung capacity; UIP = usual interstitial pneumonia; VC = vital capacity.