| COP | Idiopathic UIP | Idiopathic cellular and fibrosing NSIP | Idiopathic fibrosing NSIP | p value |
---|---|---|---|---|---|
Age (years) | 68 (43–79) | 64 (34–75) | 71 (56–75) | 50 (28–67) | ns |
Sex (male/female) | 5/2 | 11/5 | 2/5 | 4/4 | ns |
Smoking (none/ex/smoker) | 3/3/1 | 6/4/6 | 5/1/1 | 4/2/2 | ns |
Spirometry: | Â | Â | Â | Â | Â |
   VC (L) | 2.79 (1.86–4.21) | 2.73 (1.14–3.60) | 2.44 (1.28–3.32) | 2.72 (1.73–3.39) | ns |
   predicted VC (%) | 101.6 (53.0–111.2) | 82.9 (43.3–112.5) | 76.6 (56.8–108.1) | 94.7 (66.9–101.5) | ns |
   FEV1 (L) | 2.17 (1.39–2.81) | 2.18 (1.04–2.67) | 1.73 (0.99–2.53) | 2.2 (1.26–2.98) | ns |
   predicted FEV (%) | 77.6 (69.8–80.0) | 83.3 (69.4–98.2) | 85.0 (60.1–96.2) | 80.9 (66.5–89.5) | ns |
Gas exchange: | Â | Â | Â | Â | Â |
   DLco (ml/min/mmHg) | 10.28 (6.39–17.81) | 8.59 (2.32–14.65) | 9.94 (7.24–14.60) | 12.18 (7.77–19.85) | ns |
   predicted DLco (%) | 58.6 (49.3–105.1) | 46.3 (14.2–97.3) | 67.5 (44.7–109.3) | 53.1 (46.8–71.9) | ns |
Lung volume: | Â | Â | Â | Â | Â |
   predicted TLC (%) | 88.3 (49.0–98.4) | 69.3 (32.6–78.7) | 68.3 (66.3–104.2) | 74.8 (62.9–96.6) | ns |
   TLC (L) | 3.41 (2.32–5.81) | 3.86 (1.27–4.78) | 4.24 (2.27–8.80) | 3.15 (2.44–4.46) | ns |
Arterial blood gases: | Â | Â | Â | Â | Â |
   PaO2 (mmHg) | 76.2 (61.3–83.1) | 80.7 (47.2–103.3) | 74.2 (70.0–86.4) | 85.4 (77.5–92.9) | ns |