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Table 4 Impact of ICS inhaler device switch: the likelihood of asthma control among switched vs. control patients during the year after the switch

From: Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control

 

Unadjusted Analysis

Logistic Regression Analysis*

 

OR (95% CI)

p Value

OR (95% CI)

p Value

Successful treatment†

0.47 (0.37–0.58)

<0.001

0.29 (0.19–0.44)

<0.001

Unsuccessful treatment‡

1.69 (1.39–2.01)

<0.001

1.92 (1.47–2.56)

<0.001

Subsequent change in ICS device

1.73 (1.39–2.16)

<0.001

1.90 (1.50–2.42)

<0.001

  1. CI = confidence interval; ICS = inhaled corticosteroid; OR = odds ratio
  2. *Adjusted for baseline confounding factors, including short-acting β-agonist use, asthma consultation rate, socioeconomic status, and prescribed ICS dose at the index date (time of ICS device switch).
  3. †Successful treatment vs. partially successful/unsuccessful treatment.
  4. ‡Unsuccessful treatment vs. successful/partially successful treatment.