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Table 1 Demographic Characteristics and summary of pulmonary function tests of the study participants*

From: Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis

Variables

Systemic Sclerosis

Controls

p value

 

sPAP < 35 mmHg

sPAP ≥ 35 mmHg

  

Participants, No.

20

20

13

 

Female/Male

16/4

17/3

10/3

 

Age, ys

55.0 ± 14.0

58.4 ± 10.7

55.3 ± 13.4

0.379

FEV1 (%predicted)

83.9 ± 12.5

87.8 ± 18.6

99.6 ± 5.3

0.425

FVC (%predicted)

84.1 ± 14.3

86.6 ± 22.2

99.0 ± 3.2

0.570

FEV1/FVC

85.6 ± 9.4

85.5 ± 6.9

76.5 ± 2.9

0.882

DLCO (%predicted)

89.9 ± 13.4

60.0 ± 21.8

101.0 ± 4.0

<0.0001

DLCO/VA (%predicted)

88.6 ± 19.9

77.6 ± 16.3

102.3 ± 3.5

0.033

PO2 (mmHg)

81.8 ± 5.0

75.5 ± 12.3

94,8 ± 1.9

0.561

PCO2 (mmHg)

38.6 ± 3.5

37.7 ± 5.8

38.8 ± 1.2

0.942

  1. * Values are given as the mean ± SD unless otherwise indicated. sPAP: systolic pressure in the pulmonary artery, FEV1: Forced Expiratory Volume in 1 sec, FVC: Forced expiratory Vital Capacity, DLCO: Diffusing Capacity of the lungs for Carbon Monoxide, VA: alveolar volume.