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Table 4 Median (mean) relative abundance of BALF proteins in saline versus LPS treated lobe in control and rhAPC treated subjects

From: Alterations in the human lung proteome with lipopolysaccharide

Protein

Control

rhAPC

P

Alpha 2-HS glycoprotein

-1.36 (-2.2)

-2.74 (-4.3)

< 0.05

α1-antitrypsin

-1.35 (-1.2)

-2.55 (-3.7)

< 0.05

Albumin

-1.3 (-2.2)

-3.6 (-4.1)

NS

Fibrinogen γ

-1.3 (-1.1)

-1.87 (-2.2)

< 0.01

Haptoglobin

3.18 (8.2)

2.06 (3.3)

NS

Immunoglobulin J chain

-2.55 (-1.7)

-14.06 (-17.0)

< 0.001

Surfactant Protein A

-1.94 (-6.0)

-20.78 (-22.5)

NS

  1. Negative fold changes represent decreases while positive fold changes represent increases; P values calculated using Wilcoxan-Rank-Sum