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Table 1 Basic characteristics and pulmonary function tests of 21 patients (females = 8; males = 13) with CF

From: Lung diffusing capacity for nitric oxide and carbon monoxide in relation to morphological changes as assessed by computed tomography in patients with cystic fibrosis

 

Mean

% Predicted

z-score

Age, yr

35 ± 9

-

-

Height, cm

176 ± 11

-

-

Weight, kg

65.5 ± 13.4

-

-

VA, L

5.45 ± 1.78

87 ± 19

-1.3 ± 2.0

DLNO, mmol × min-1 × kPa-1

34.7 ± 12.2

71 ± 19

-2.3 ± 1.5

DLCO, mmol × min-1 × kPa-1

9.1 ± 2.7

83 ± 18

-1.3 ± 1.4

DLNO/DLCO

3.8 ± 0.4

§

§

KNO, mmol × min-1 × kPa-1 × L-1

6.34 ± 0.91

84.7 ± 11.9

-1.9 ± 1.6

KCO, mmol × min-1 × kPa-1 × L-1

1.69 ± 0.18

81.6 ± 7.4

-1.2 ± 0.6

Dm, mmol × min-1 × kPa-1

17.6 ± 6.2

§

§

Vc, mL

80 ± 25

§

§

FEV1, L

2.58 ± 1.35

66 ± 28

-2.7 ± 2.3

IVC, L

4.18 ± 1.56

88 ± 23

-1.1 ± 2.1

FEV1/VC, %

59 ± 13

73 ± 15

-3.2 ± 1.8

RAW, kPa × s × L-1

0.43 ± 0.25

$

$

SRAW, kPa × s

1.97 ± 1.24

$

$

ITGV, L

4.14 ± 1.10

128 ± 27

1.6 ± 1.6

RV, L

2.90 ± 1.06

162 ± 51

2.9 ± 2.5

TLC, L

7.08 ± 1.69

108 ± 15

0.8 ± 1.4

  1. §Not computed due to lack of sufficient and standardised data
  2. $ Not computed, as reference equations are not commonly used for interpretation
  3. Data are presented as mean ± SD. Abbreviations: VA = alveolar volume, DLNO = lung diffusing capacity for nitric oxide, DLCO = lung diffusing capacity for carbon monoxide, KNO = nitric oxide transfer coefficient, KCO = carbon monoxide transfer coefficient, Dm = membrane diffusing capacity, Vc = pulmonary capillary blood volume, FEV1 = forced expiratory volume in 1 s, VC = maximal inspired vital capacity, RAW = airway resistance, SRAW = specific airway resistance, ITGV = intrathoracic gas volume, RV = residual volume, TLC = total lung capacity. Prediction equations for VA according to [15], for DLCO/KCO according to [16], for DLNO/KNO according to [17], and for lung volumes according to [21].
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BMC Pulmonary Medicine

ISSN: 1471-2466

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