Table 2 Gene expression by qRT-PCR in lung samples after inhalation, adjusted mRNA transcript values (number/μl cDNA)a
From: Tolerability of inhaled N-chlorotaurine in the pig model
1% NCT | 5% NCT | NCT + NH4Cl | NaCl | ||
|---|---|---|---|---|---|
HO-1 | near carina | 2656 (1878) | 1772 (1282) | 3200 (3018) | 1469 (1737) |
peripheral | 5003 (2608) | 2833 (2639) | 4300 (3416) | 2044 (1717) | |
TNF alpha | near carina | 394.8 (157) | 370.8 (190) | 635.6 (440) | 400.7 (198) |
peripheral | 214.6 (79) | 185.2 (72) | 243.0 (286) | 344.6 (316) | |
IL-1-beta | near carina | 82.0 (104) | 116.5 (87) | 73.4 (39) | 75.0 (139) |
peripheral | 77.8 (62) | 58.3 (71) | 247.6 (403) | 164.0 (266) | |
IL-8 | near carina | 469.6 (395) | 704.5 (991) | 191.2 (93) | 274.0 (475) |
peripheral | 846.2 (506) | 772.5 (895) | 1426.2 (1670) | 779.0 (1187) |