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Table 1 Clinical Characteristics

From: IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis

  Control
(n = 16)
Asthma Mild-moderate
(GINA 1 = 6, GINA 2–3 = 6)
Asthma Severe
(GINA 4 = 6, GINA 5 = 6)
Eosinophilic Bronchitis
(n = 7)
Age (yrs)~ 32.2 (2.3) 37.3 (3.7) 51.0 (4.3)* 53.6 (6.2)*
Sex M:F 7:9 7:5 4:8 6:1
Atopy (%) 46 83** 67** 43
Disease Duration (yrs) N/A 22.0 (3.8)** 30.4 (4.9)** 8.4(1.8)
BDP Equivalent (mcg) N/A 355 (132) 1633 (175) 1149(420)
Oral Prednisolone
(mg/24 hrs)
N/A N/A 5.6 (2.0) 0
ENO (50)
(Ppb) #
18 [9–37] 28 [19–46] 19 [14–25] 34 [18–64]
PC 20 (mg/ml)# >16 1.4 [0.4–4.9]** 0.45 [0.1–1.7]** >16
FEV 1 % predicted~ 109 (3.3) 90 (8.7) 78 (6.0)* 95.7(5.6)
FEV 1 /FVC~ 86.3(1.7) 79 (3.4) 72 (3.5)* 80.0(4.4)
Induced sputum     
Eosinophils (%)# 0.7 [0.2–2.7] 2.2 [0.4–13.0]* 1.9 [0.8–4.6]* 4.6 [1.3–16.5]*
Neutrophils (%)~ 43 (12.6) 46 (9.9) 66.5 (7.1) 43.5(5.6)
  1. ~ mean (SEM), # geometric mean (95% confidence interval), N/A not applicable
  2. *p < 0.05 vs. control, **p < 0.05 vs. control and/or EB