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Table 5 MIC Range, and MIC50 and MIC90Values of Common Respiratory Pathogens in the ME Population

From: Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia

  Tigecycline Levofloxacin
Isolate n MIC Range MIC50 MIC90 n MIC Range MIC50 MIC90
Streptococcus pneumoniae (penicillin susceptible) 45 0.030, 0.120 0.060 0.060 45 0.250, 2.000 1.000 1.000
Penicillin-intermediate S. pneumoniae 8 0.060, 0.060 NA NA 8 1.000, 1.000 NA NA
Penicillin-resistant S. pneumoniae 5 0.060, 0.060 NA NA 5 1.000, 2.000 NA NA
Haemophilus influenzae 18 0.120, 0.500 0.250 0.500 18 0.120, 0.120 0.120 0.120
Haemophilus parainfluenzae 13 0.250, 0.500 0.500 0.500 13 0.120, 0.120 0.120 0.120
Klebsiella pneumoniae 11 0.250, 2.000 0.500 1.000 11 0.120, 0.500 0.120 0.120
Staphylococcus aureus (all non-MRSA) 15 0.120, 0.250 0.120 0.120 15 0.120, 0.250 0.120 0.250
  1. MRSA: methicillin-resistant Staphylococcus aureus