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Table 7 Drug-Related Adverse Events that Occurred in ≥ 3% of Patients (mITT Population), Number of Patients (%)

From: Efficacy and safety of tigecycline versus levofloxacin for community-acquired pneumonia

Body System Tigecycline Levofloxacin Total Fisher Exact
Adverse Event (N = 216) n (%) (N = 212) n (%) (N = 428) n (%) P-Value
Any adverse event 96 44.4 62 29.2 158 36.9 0.001*
Body as a whole 10 4.6 10 4.7 20 4.7 1.000
Cardiovascular system 9 4.2 5 2.4 14 3.3 0.416
Digestive system 70 32.4 34 16.0 104 24.3 <0.001*
   Diarrhoea 15 6.9 14 6.6 29 6.8 1.000
   Nausea 54 25.0 16 7.5 70 16.4 <0.001*
   Vomiting 31 14.4 10 4.7 41 9.6 <0.001*
Haemic and lymphatic system 7 3.2 4 1.9 11 2.6 0.544
Metabolic and nutritional 15 6.9 16 7.5 31 7.2 0.854
  1. Some subjects had more than 1 drug-related adverse event.
  2. *Significant between-group difference at 0.05 level.