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Figure 5 | BMC Pulmonary Medicine

Figure 5

From: Protective effect of geranylgeranylacetone, an inducer of heat shock protein 70, against drug-induced lung injury/fibrosis in an animal model

Figure 5

Evaluation of cytoprotective effect of GGA against lung injury by in vivo TUNEL assay. Evaluation of cytoprotective effect of GGA against lung injury by in vivo TUNEL assay of the lungs from treated mice on BLM day 1 and day 3. Representative lung sections from day3 vehicle-treated BLM mice (A) and GGA-treated BLM mice (B) were shown. TUNEL-positive cells (arrows in A and B) were counted in the whole area of the mid-sagittal section (day 1 in C and day 3 in D), expressed per total cell counts. At least five mice were prepared for each group in each experiment. Data shown represent the mean ± SEM from two independent experiments. *Statistically significant difference (p < 0.05) in comparison. BLM, bleomycin; GGA, geranylgeranylacetone.

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BMC Pulmonary Medicine

ISSN: 1471-2466

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