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Table 3 Univariate regression analysis (one variable at a time) for relationship between lung function and TLR4 wild-type and polymorphic groups

From: Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index

Lung Function Model I
FEV1
Model II
FVC
Model III
FEV1/FVC
Model IV
FEF25_75
Variable Parameter Estimate (SE) Parameter Estimate (SE) Parameter Estimate (SE) Parameter Estimate (SE)
Age, yrs -0.033 (0.001)*** -0.036 (0.001)*** -0.001 (0.000)*** -0.041 (0.002)***
BMI (reference is normal)     
   Overweight 0.074 (0.055) 0.134 (0.067)* -0.010 (0.004)* 0.057 (0.075)
   Obese -0.060 (0.057) -0.106 (0.069) 0.003 (0.004) 0.096 (0.077)
Smoking status (reference is never smoker)     
   Ever smoker -0.032 (0.044) 0.012 (0.054) -0.011 (0.003)** -0.151 (0.060)*
Sex (reference is female)     
   Male 1.031 (0.037)*** 1.336 (0.044)*** -0.011 (0.003)** 0.934 (0.056)***
TLR4299 (reference is wild-type)     
   polymorphic groups 0.134 (0.064)* 0.185 (0.078)* -0.002 (0.004) 0.091 (0.088)
Grain Dust (reference is not exposed)     
   Exposed 0.299 (0.045)*** 0.426 (0.054)*** -0.011 (0.003)** 0.214 (0.061)**
Household Smoking (Reference is No)     
   Yes 0.021 (0.069) 0.001 (0.083) 0.004 (0.005) 0.037 (0.093)
  1. *** p < 0.001; ** p < 0.01; * p < 0.05
  2. Normal: <25; Overweight: 25-30; Obese: >30